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What Does An Increased Igg Mean?

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Hi everyone,


I had a few tests done that my rheumatologist wanted and when I went and saw my family doctor, she had also received a copy and mentioned that my IgG test was raised above normal, and then carried on talking about something else.


I don't see my rheumatologist until the end of November as not all my tests will be back until then, but I did wonder what a raised IgG test mean't as I am having trouble looking it up.


It is only marginally over normal so I am not worried, but more curious.





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Hi Irene,


From what I could find, Immunoglobulin G (IgG) is the major circulating antibody which enters tissues freely, and participates in diverse immune events. When I looked it up on the Sclero A to Z website it was always in reference to specific ANA patterns. So, my guess (and that is just it, a guess, as I am not a doctor) is that yours being elevated is just another indicator that something is going on.


I hope that helps.


Warm wishes,



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Sorry I'm late in responding to this but I needed to find that "just right" information on IgG. When I started IVIg infusions about 1.5 years ago my niece who's an RN sent me some great information. One thing I found very interesting in her information and it's also in the link I'm providing is "IgG antibodies are the only type of antibody that can cross the placenta. Therefore, the IgG antibodies of a pregnant woman can also help protect her baby (fetus). "


As Heidi said, IgG is an antibody that is produced by the immune system to help fight disease. It is the most abundant of the five major types antibodies: IgA, IgG, IgM, IgD, IgE. These antibodies are called immunoglobulins. Here's some info from WebMD.

"A person whose immune system produces low levels of antibodies may be at an increased risk of developing repeated infections."

"Levels of IgG also increase in IgG multiple myeloma, long-term hepatitis, multiple sclerosis (MS), and some autoimmune diseases."


It's all a learning process. I learn something new everyday and this forum is a great source for information and for that question that allows one to seek out new information.


Big Hugs,

Janey Willis

ISN Support Specialist

(Retired) ISN Assistant Webmaster

(Retired) ISN News Director

(Retired) ISN Technical Writer for Training Manuals

International Scleroderma Network (ISN)

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Thanks so much Janey for finding that information for me!


I had such a hard time trying to find anything about it, and when I did I didn't understand it.

Of course I am hoping when I see the rheumatologist in 3 weeks he will explain it to me, but of course we all like to know what is going on with our bodies, don't we!


There is so much to know and understand, sometimes I don't know where to begin, but this forum has proved a wonderful place for me too.


thanks again Janey,




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