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Just a silly question but can ana test change from positive to negative or is it that once they are positive they stay positive?

 

How many people have gotten a diagnosis without the positive ana test

 

sorry just curious after reading a couple of posts


Kindest Regards

 

Sharon

 

Diagnosis Scleroderma-crest, Scolliosis, Asthma, ILD, Plueral Fibrosis, GERD, Hiatus hernia, Anticardiolipin positive, ANA positive

 

a little bent and broken and almost beyond repair!

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Sharon,

My ANA test has been positive and negative at different times. When I was diagnosis at Johns Hopkins the ANA test I had done a year earlier was negative and the rheumatologist still gave me the diagnosis of CREST. The ANA test that was done after I saw her was very high! The body is an amazing thing!

Take Care!

Nan

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Hi Sharon, when I was first diagnosed my ANA was 1:640,(nucleolar pattern) , next test two months later was 1:160, and one after that was negative, so they certainly can go from positive to negative. However, even though is negative am still getting progression of skin tightening and other new symptoms , so doesn't , at least in my case, seem to be realted to disease activity.

lizzie

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I think it varies more often than not. Mine has been positive (speckled pattern) and negative over the last couple of years. The Scl-70 has stayed positive even though my ANA was negative last time. Go figure!

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Thanks for the rely because I was a little confused seeing this written as the rheumatologist that I saw said that a positive is a positive and doesn't ever change that is it did change that is was that the lab was an inferioir one and the tests werent being carried out properly.

 

hmm no wonder I am lookng at going to another rheumatologist for a opinion


Kindest Regards

 

Sharon

 

Diagnosis Scleroderma-crest, Scolliosis, Asthma, ILD, Plueral Fibrosis, GERD, Hiatus hernia, Anticardiolipin positive, ANA positive

 

a little bent and broken and almost beyond repair!

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I found this discussion of an ANA change through a Google search, and it was so helpful. Thanks for asking it! I just had the same thing happen.

 

I had a very high positive ANA test --centromere pattern--a couple of times 4 years ago, but only had symptoms of Raynaud's and aching and fatigue, and nothing else developed over the next 3 years. I relocated to a warm climate a year ago but haven't located a rheumatologist yet. I have developed severe dry mouth and eyes so I was trying to get a referral from my general practitioner to a rheumatological clinic at a university research facility for an assessment. The clinic asked for new tests, and the blood work shows nothing. Now I'm worried the clinic won't take me. But this discussion gives me the information that I should keep working at it and not assume a miracle has happened!

 

Thanks so much.

Gracie

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Somehow I totally missed this discussion and I would now like to Welcome Gracie to our forums. Have you been diagnosed with Scleroderma? What did your other doctors tell you that they thought you might have? I would think that the clinic will take the time to do several tests on you and make a decision on their own findings. My tests have always come back negative so far. Even if I am in a flare at the time. I really don't know what the doctors see when one person is having the same symptoms as another yet there ANA's are different. Chime in with any other topics you would like to hear about. Now I need to get back to jumping around topics to see what else I have missed. Sheryl


Strength and Warmth,

Sheryl

 

Sheryl Doom

ISN Support Specialist

(Retired) ISN Chat Moderator

International Scleroderma Network (ISN)

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I seem to have missed this, too, Sheryl. Sorry, Gracie, but welcome to the forums. I am glad Google delivered you to our midst. Actually, that's what brought me here, too. Good luck with trying to get into the new clinic. Is it possible you can get copies of the old test results and notes and send them directly to the clinic? At least you are finding it more comfortable in your warmer climate and with any luck, your symptoms won't get worse. It is important to keep watch, however and a good rheumatologist, even if it is not at your preferred clinic, is a valuable ally. Good luck and again, welcome.


Warm wishes,

Jefa

 

Carrie Maddoux

(Retired)ISN Sclero Forums Support Specialist

(Retired)ISN Sclero Forums UK Chat Host

International Scleroderma Network (ISN)

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