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Minocycline, Antibiotic

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Scleroderma Clinical Trials: Completed, Negative Results/Minocycline

Warning: Minocycline (doxicycline) treatment has been proven to be ineffective for the treatment of systemic scleroderma by reliable scientific study

Minocycline is not effective in systemic sclerosis: results of an open-label multicenter trial.The degree of change in the MRSS (modified Rodnan skin thickness score) was similar to that expected in the natural course of this disease. Based on these data, minocycline is not an effective therapy for SSc. PubMed. Arthritis rheumatologist. 2004 Feb;50(2):553-7.


Warm wishes,

Jefa

 

Carrie Maddoux

(Retired)ISN Sclero Forums Support Specialist

(Retired)ISN Sclero Forums UK Chat Host

International Scleroderma Network (ISN)

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There have been several inquiries about minocycline lately due to an article in a magazine. Jefa posted this message last week so I thought I would bring it back up. There have been a couple of studies with scleroderma and minocycline. You can read about all the studies at the first link provided in Jefa's posting. In a nutshell,

 

Minocycline (doxicycline) treatment has been proven to be ineffective for the treatment of systemic scleroderma by reliable scientific study.

 

I know we are all looking for that miracle drug, but apparently this isn't it.

 

Big Hugs,


Janey Willis

ISN Support Specialist

(Retired) ISN Assistant Webmaster

(Retired) ISN News Director

(Retired) ISN Technical Writer for Training Manuals

International Scleroderma Network (ISN)

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I tried minocycline when I was first sick. My SD continued to progress and progress rapidly. The minocycline did nothing but disturb my stomach.


Lucy

Diffused Scleroderma

Diagnosed Dec/06

First Sympton Nov/05

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