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ozzy69

Methotrexate

16 posts in this topic

Hi Everyone,

 

I went for my three months check-up yesterday. Lungs test look good! Raynaud's worst with more swelling of hands and feet. Been feeling flu like for awhile. My rheumatologist has decided to start me on methotrexate. She said I should take it on a day that I would have a couple days to feel better. She is also giving me folic acid. How long to you feel bad and what should I expect?

 

Thanks so much.

 

Nina Lynn

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I haven't heard if my doctor is going to put me on this yet. But what I have heard is if you can get the injection methotrexate instead of the pill form. With this you then won't have to deal with nausea that you will apparently have with the pill form. I have also seen people post that they take it on a Friday so they have the weekend to go through the side effects. I have also heard that you are pretty wiped out too but I'm not sure. Good luck and you and I will have to share with each other on how it's going if I get put on it too.

 

Warm hugs,

 

Peggy

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Thanks Peggy!

 

If they put you on it we can compare notes as you said. I thought about taking it on Monday nights. I am off on Tuesdays. I hate to take it on the weekend. I am off of work but I stay really busy with my boys. I would hate to be sick all weekend. She gave me the pill form. I hope it does not upset my stomach too bad.

 

Please keep me informed,

 

Hugs,

Nina Lynn

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Hi Nina Lynn,

 

Have you checked out the section on Methotrexate? The second article down provides a link to a site with patient information that might be helpful. All the reading I've done seems to indicate adding the folic acid really helps with the nausea, etc.

 

Best wishes,


Jeannie McClelland

(Retired) ISN Director of Support Services

(Retired) ISN Sclero Forums Manager

(Retired) ISN Blog Manager

(Retired) ISN Assistant News Guide

(Retired) ISN Artist

International Scleroderma Network

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Hi Nina Lynn,

 

I nearly had a message typed out for you, when it was necessary for me to go attend to something else!

 

Peggy and you seem to have this all solved, I see! Good deal!

 

I started the methotrexate (MTX) regimen fourteen years ago, in order to treat my severe case of psoriasis.

 

I was just going to let you know that I took the pills daily, short term. I then switched to the liquid and drank it in my juice, which I seemed to always have a problem with psychosomatically, so that method didn't last over two years.

I will say, however, that the new, young dermatologist that prescribed it to me neglected to also prescribe for me folic acid. As a result, I will again stress that knowledge is power!

 

For the last ten and one half years of my need for treatment, I injected subcutaneously, alternating thighs every other week. Like you, I opted to inject on Mondays, so that a had enough time to feel better by the week's end!

 

I was monitored every six weeks via blood work for quite some time. It's been four years (next month), since I stopped using MTX. Unfortunately, I'll likely be starting back up with it, due to having strep throat, which triggered guttate psoriasis.

 

I did also want to add that I also had the option to go to the clinic weekly, where I could get the injection at no charge. However, I chose to do it myself, as I would inject just before bedtime, which also seemed to help with the nausea.

 

Please keep us posted, Jensue!


Special Hugs,

 

Susie Kraft

ISN Support Specialist

ISN Chat Host

International Scleroderma Network (ISN)

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I use the injectable kind of methotrexate - mainly because the pill form was hurting my gut, not so much there was nausea. Unfortunately though, I don't have any better days with it and my CRP is staying high in spite of it. But it is the drug that is associated with improving CREST so I guess I will stick with it. It does give me a cough though.

 

Lynne

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Hi Nina Lynn

 

I take methotrexate in tablet form 25mg once a week and I have never had any side effects. Because I can't work because of the sclero it doesn't matter what day I take it....so I take it on Tuesday and the folic acid on Friday. The doctor did tell me to take 15mg in the morning and 10mg at night. When I first started it I was very nervous waiting for the side effects but they never happened.

Hope it goes well for you.

 

Helen

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Susie, Lynne, Jeannie and Helen,

 

Thanks so much for your responses. Starting something new always makes me nervous. I seem to get back side effects from many meds. I am tired of feeling bad and hopefully this will help.

 

Susie,

 

You said you did your injections at night. Did you have any problems sleeping? I do work on Wednesday. I work three days a week: Mondays, Tuesdays, and Fridays. Hopefully starting the med on Monday night will work for me. I just hate to not feel well on the weekends.

 

Thanks again everyone. It helps so much to hear about how treatments have worked for others.

 

Big Hugs,

 

Nina Lynn

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Nina,

I see you have already some great information and advice. I'll just add a little more from personal experience. I took MTX for 3 years - starting on pills then switched to injections after 4 months. Once I got over the fear of self-injection (it only took two shots), I actually found I preferred the shots more than the pills. It's easier on your liver and stomach. I was a little queasy with the pills but had absolutely no side effects with the shots. I took my shot on Sunday morning and then enjoyed the day. I also took daily folic acid.

 

Hope you do well on it. It sure stopped my disease in its tracks.

 

Big Hugs,


Janey Willis

ISN Support Specialist

(Retired) ISN Assistant Webmaster

(Retired) ISN News Director

(Retired) ISN Technical Writer for Training Manuals

International Scleroderma Network (ISN)

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Hello Nina Lynn,

 

My daughter was on methotrexate (MTX) for about a year. She tolerated it quite well. This drug in scleroderma is very helpful It prevents contractures, meaning stiffness of the joints. She was given a weekly dose every Saturday, and folic acid on Friday or Monday. Anything will do. Don't neglect physical therapy.

 

Goodluck,

 

m/o ashu

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Hi Ozzy 69,

 

I have been taking methotrexate for a year now and as long as you take your folic acid everyday you won't get sick on the day you take the methotrexate. I didn't take the folic acid the very first time I took the methotrexate. BOY DID I GET SICK!

I feel like the methotrexate has helped.

 

Hugs,

 

pooder13

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Hi Nina Lynn,

 

You asked me if I had any problems sleeping as a result of the MTX.

Not at all. The only other thing I would suggest, is that you might want to inject on Wednesday nights and by the weekend, you'll do just fine. Of course, you may have no trouble at all!

 

Wish you the best!


Special Hugs,

 

Susie Kraft

ISN Support Specialist

ISN Chat Host

International Scleroderma Network (ISN)

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I have been on methotrexate since 1/07 and have tolerated it quite well. I started with 10mg weekly and now I'm up to 25mg. My rheumatologist did prescribe folic acid along with it which I take daily. It has never caused me to be nauseous. I too have my bloodwork checked evey 6 weeks to ensure I am tolerating it well. I started taking it on Friday so that in the event I did get the "wiped out" feeling I had the weekend to get better. I now take it on Sunday without issue.

 

Best wishes!


I may have Scleroderma, but Scleroderma doesn't have me!

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Thanks so much to everyone for thier responses! I am going to start on Monday. I will keep everyone updated on how it goes.

 

Thanks again,

Nina Lynn

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Hi.

 

I started methotrexate (MTX) with folic acid on Saturday, and all is well. I did not get any side effects (nausea), and am well pleased. I take folic acid every day along with 10mg prednisone, and neutronin 2x daily for the nerve pain in my feet. The Raynaud's is really bad there, too.

 

I keep losing weight, although I eat like a horse. I used to weigh 115 in the fall, then in January I was 105, and now I am 98 lbs. I have a fitness friend who, after hearing my battle with trying to keep my weight, said she will never say she wants to lose weight again! We laughed.

 

Still having trouble with joint contractures, but hoping the MTX will help. I understand it can take up to 3 months to kick in. I am going to consult with the cardiologist sometime this week concerning his opinion on having an angiogram and CT scan, as my rheumatologist thinks it may be a good thing due to the echo results.

 

Hoping your experience with MTX is a good one.

 

Stay strong.

 

Honey

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Hi Everyone,

 

Thanks so much for your replies! I started the MTX on monday night. I woke up tuesday feeling fine, but later that day I started to some nausea and felt really tired. The next day I was fine a little nausea and not as tired. My fibro pain seemed to be worse on Tuesday. Things went well so far.

 

Thanks again,

Nina Lynn

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