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New Member - Tested Positive for Scleroderma after 3 miscarriages

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Hi Josephine,

I'm so sorry to hear about all the miscarriages your daughter has experienced. I know exactly how she feels. If it wasn't for me seeing a fertility specialist I would have never known to be tested since I don't have any symptoms. It's hard to believe that doing something as easy as taking one baby aspirin a day can help prevent miscarriages according to my fertility doctor and rheumatologist. I also tested positive for something called an "MTHFR" gene mutation (which pretty much means my body doesn't produce the enzymes required to process Folic Acid, which is crucial while pregnant). So I was put on high doses of Folic Acid to help with that. I don't know if Scleroderma runs in the family, but I just found out that my Grandma was told a few years ago that she may have it (due to skin thickening, and Raynaud's). Please keep me posted on you daughter. I'm seeing my rheumatologist next week to get the results for all the tests they ran, then hope to conceive a week after that! Hope you have a great holiday.



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  • 6 years later...

I know this is an old topic, but I am curious if Jennifer, who was concerned about having a positive SCL-70 without symptoms ever did end up being diagnosed with scleroderma? Did you end up having a successful pregnancy? I am in the same boat, positive RNA polmerase and esophageal dysmotilitiy but that is all for now. Really want to try for another baby but scared and would love to know your outcome.


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  • 3 weeks later...

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