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August 2014 Autoimmune News

Sjögren's syndrome (pSS): still not fully understood disease. Laboratory biomarkers and useful imaging tools for predicting the development of complications associated with Sjogren's. PubMed, Rheumatol Int, 2014 Jul 2. (Also see Sjogrens Syndrome)

Cytokine profiles in polymyositis (PM) and dermatomyositis (DM) complicated by rapidly progressive or chronic interstitial lung disease (ILD). Cytokine levels were high, especially in the ILD subset, and are associated with global disease activity in PM/DM. PubMed, Rheumatology (Oxford), 2014 Jun 26. (Also see Dermatomyositis and Polymyositis)

Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset. The presence of anti-NXP2 autoantibodies substantially increases the risk of calcinosis across all ages and is associated with disease severity. PubMed, Rheumatology (Oxford), 2014 Jul 1. (Also see Dermatomyositis Symptoms and Calcinosis)

There is still a care gap in osteoporosis management for patients with rheumatoid arthritis. Although compliance with current osteoporosis guidelines remains low among all patients with rheumatoid arthritis, higher risk patients were more likely to have a bone mineral density test and receive treatment for osteoporosis. PubMed, Joint Bone Spine, 2014 Apr 2. (Also see Rheumatoid Arthritis and Osteoporosis)

Pain in rheumatoid arthritis: a critical review. The management of pain requires various approaches that include pharmacological analgesia and biological and non-biological treatments and although joint replacement surgery can significantly improve RA-related pain, it may only be available to patients with the most severe advanced disease. PubMed, Reumatismo, 2014 Jun 6;66(1):18-27. (Also see Rheumatoid Arthritis and Pain Management)

Vasculitis: determinants of disease patterns. Certain antigens, including infectious agents, might become disease-relevant and vascular diversity could influence disease phenotypes and the spectrum of vascular inflammatory diseases. PubMed, Nat Rev Rheumatol, 2014 Jun 17. (Also see Vasculitis)

Lupus mesenteric vasculitis (LMV): Clinical features and associated factors for the recurrence and prognosis of disease. The clinical characteristics of (LMV) and the potential factors and appropriate treatments associated with disease relapse and prognosis. PubMed, Semin Arthritis Rheum, 2014 Jun;43(6):759-66. (Also see Vasculitis and Systemic Lupus Erythematosus)

Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder (MDD). The Chinese MFI-20 is a valid and reliable instrument for the assessment of fatigue in MDD patients with residual symptoms. The construct of fatigue in MDD seems to be different from that in medical conditions. Comprehensive Psychiatry, 06/30/2014. (Also see Fatigue and Depression)

Functional Impact of a Spectrum of Interstitial Lung Abnormalities (ILAs) in Rheumatoid Arthritis (RA). Improved risk stratification and detection of ILAs will provide a therapeutic window that could improve RA-ILD (interstitial lung disease) outcomes. CHEST Journal 2014;146(1):41-50. (Also see Rheumatoid Arthritis)

Cerebral large vessel vasculitis in systemic lupus erythematosus. A female patient with the diagnosis of SLE presented with stroke-like symptoms, headache and vertigo, and palpable purpura on her legs. Further investigations revealed that she suffered from both vasculitis of the cerebral large vessels and coexisting cutaneous small-vessel vasculitis. PubMed, Lupus, 2014 Jun 26. (Also see Systemic Lupus Erythematosus and Vasculitis)

Go to Autoimmune News: July 2014

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