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July 2015 Autoimmune News

Missing link between brain and immune system found. A team of researchers has discovered the “missing” link between the brain and the immune system that may better treat neurological diseases such as Alzheimer’s and multiple sclerosis in the near future. NHS Choices, 06/08/2015. (Also see Multiple Sclerosis)

Antibodies to interferon-inducible protein-16 in primary Sjögren's syndrome are associated with markers of more severe disease. Anti-IFI16 antibodies are a prominent specificity in primary SS and are associated with markers of severe disease. PubMed, Arthritis Care Res (Hoboken), 06/02/2015. (Also see Diagnosis of Sjögrens)

Diagnostic properties of ultrasound of major salivary glands in Sjögren's Syndrome: a meta-analysis. The quality of current studies is low, thus not allowing to judge the likelihood of salivary gland ultrasonography as a reliable and practical tool in diagnosing Sjögren's Syndrome. PubMed, Oral Dis, 05/18/2015. (Also see Diagnosis of Sjögrens)

Aortic regurgitation is common in ankylosing spondylitis - time for routine echocardiography evaluation? As aortic regurgitation and/ or conduction abnormalities might cause insidious symptoms, both electrocardiography and echocardiography evaluation should be part of the routine management of patients with ankylosing spondylitis. PubMed, Am J Med, 06/04/2015. (Also see Ankylosing Spondylitis and Diagnosis of Heart Involvement)

Clinicopathological features of sarcoidosis manifesting as generalized chronic myopathy. Muscle biopsy specimens revealed an active inflammatory process and functional improvement after immunomodulatory treatment was significantly better in patients with short disease durations. PubMed, J Neurol, 2015 Apr;262(4):1035-45. (Also see Sarcoidosis)

Frequency of Migraine Headaches in Patients With Fibromyalgia. Migraine headaches are common in patients with fibromyalgia and these conditions can significantly increase a patient’s cumulative disease burden. PubMed, Headache, 05/21/2015. (Also see Fibromyalgia)

Is it necessary to strictly diagnose fibromyalgia syndrome (FMS) in patients with chronic widespread pain (CWP)? Future research should be directed toward classification of CWP to provide guidance to clinicians in selecting effective therapies. PubMed, Clin Rheumatol, 05/26/2015. (Also see Fibromyalgia)

Early signs of arthritis can be found in the mouth. A common gum disease may indicate a person’s risk of developing rheumatoid arthritis later in life. The University of Adelaide News, 05/04/2015. (Also see Periodontal Disease and Autoimmunity)

Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis. Standard-dose and high-dose biological drugs are associated with an increase in serious infections in rheumatoid arthritis, although low-dose biological drugs are not. The Lancet, 05/19/2015. (Also see Biologic Agents)

Effect of menopause hormone therapy on disease progression in systemic lupus erythematosus: A systematic review. Hormone therapy in menopausal patients with systemic lupus erythematosus appears to be well tolerated. PubMed, Maturitas, 2015 Jun;81(2):276-281. (Also see Research on Systemic Lupus Erythematosus)

Go to Autoimmune News: June 2015

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