The Prevalence of Individual Histopathologic Features Varies according to Autoantibody Status in Muscle Biopsies from Patients with Dermatomyositis (DM). The prevalence of different histological features varies according to autoantibody status in DM and muscle biopsy features are similar in anti-Jo1 patients with and without a rash. Journal of Rheumatology, 07/14/2015. (Also see Dermatomyositis)
Investigation of Lung Involvement in Connective Tissue Disorders (CTD). The investigation of lung involvement in CTDs requires adequate skills in the ambit of a multidisciplinary approach and an extended spectrum of diagnostic tools. PubMed, Respiration, 06/26/2015. (Also see Connective Tissue Disease and Pulmonary Fibrosis Diagnosis)
A review of salivary gland histopathology in primary Sjögren's syndrome with a focus on its potential as a clinical trials biomarker. The role of histopathology as a biomarker for stratification and response to therapy is reviewed. PubMed, Ann Rheum Dis, 06/01/2015. (Also see Sjögren's Syndrome Research)
Quality of Sexual Life in Women with Primary Sjögren Syndrome (pSS). Both premenopausal and postmenopausal women with pSS have a worse sexual quality of life as they have a greater prevalence of dyspareunia. PubMed, J Rheumatol, 07/01/2015. (Also see Sexuality and Scleroderma and Symptoms and Complications of Sjögren's Syndrome)
Active disease is independently associated with more severe anxiety rather than depressive symptoms in patients with systemic lupus erythematosus (SLE). Anxiety is more common in lupus patients than in healthy controls and its severity is independently associated with more active SLE regardless of the presence or absence of concomitant depression. PubMed, Lupus, 06/17/2015. (Also see Anxiety and Attitude and Research on Systemic Lupus Erythematosus)
Anti–CII antibody as a novel indicator to assess disease activity in systemic lupus erythematosus (SLE). Anti–dsDNA Abs and complement factors have been used as indicators of lupus activity and therefore, anti–CII Ab could be a novel indicator for monitoring activity of SLE. PubMed, Lupus, 06/05/2015. (Also see Antibodies in Lupus)
B-cell survival factors in autoimmune rheumatic disorders. The information on the use of biologic agents blocking B-cell activating factor and A proliferation inducing ligand for patients with lupus, rheumatoid arthritis, Sjögren’s syndrome and myositis has been updated. Therapeutic Advances in Musculoskeletal Disease, 07/17/2015. (Also see Biologic Agents)
Contribution of Dendritic cells (DCs) to the autoimmune pathology of Systemic Lupus Erythematosus. In this review article the authors discuss the most relevant data relative to the contribution of DCs to the triggering of SLE. PubMed, Immunology, 07/17/2015. (Also see Dendritic Cells)
The effect on treatment response of fibromyalgic (FRA) symptoms in early rheumatoid arthritis (RA) patients: results from the ESPOIR cohort. Patients with FRA and RA will have a similar response to treatment, but may miss the target of remission or low disease activity. PubMed, Rheumatology (Oxford), 07/17/2015. (Also see Treatments for Rheumatoid Arthritis and Rheumatoid Arthritis in Overlap)
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