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April 2016 Autoimmune News

Musculoskeletal manifestations of the antiphospholipid syndrome (APS). Musculoskeletal complications are consistently reported in APS patients, not only causing morbidity and mortality, but also affecting their quality of life. PubMed, Lupus, 02/27/2016. (Also see Antiphospholipid Syndrome)

Inadequate response or intolerability to oral methotrexate (MTX): Is it optimal to switch to subcutaneous (SC) methotrexate prior to considering therapy with biologics? SC MTX can prove to be more efficacious in patients refractory to oral MTX therapy or in patients experiencing severe gastrointestinal adverse effects. PubMed, Rheumatol Int, 03/02/2016. (Also see Immunosuppressants and Treatments for Rheumatoid Arthritis)

Urinary dedifferentiated podocytes as a non-invasive biomarker of lupus nephritis (LN). Urinary dedifferentiated podocytes were shown in active LN, and their protein levels correlated with proteinuria and histological features in LN. PubMed, Nephrol Dial Transplant, 02/29/2016. (Also see Symptoms and Complications of Lupus)

Bone and Celiac Disease. Adequate calcium and vitamin D supplementation are also recommended to optimize bone recovery, especially during the first years of gluten free diet. Springer Link, 02/13/2016. (Also see Celiac Disease and Vitamin D Deficiency)

Is Bariatric Surgery a Trigger Factor for Systemic Autoimmune Diseases? A causal relationship is difficult to establish because factors that could trigger autoimmune diseases are multiple, including genetic susceptibility, time elapsed until achievement of ideal weight, and vitamin deficiencies. PubMed, J Clin Rheumatol, 2016 Mar;22(2):89-91. (Also see Autoimmunity)

Acute Respiratory Events in Connective Tissue Disorders (CTDs). In CTDs the lungs significantly contribute to morbidity and mortality, since they constitute a common site of disease involvement. PubMed, Respiration, 03/04/2016. (Also see Connective Tissue Disease)

Differentiation between early rheumatoid and early psoriatic arthritis by the ultrasonographic (US) study of the synovio–entheseal complex of the small joints of the hands. The US involvement of synovio–entheseal complex and US extrasynovial features may be helpful in the differential diagnosis between early rheumatoid and early psoriatic arthritis. PubMed, Clin Exp Rheumatol, 03/03/2016. (Also see Diagnosis of Rheumatoid Arthritis and Psoriasis and Psoriatic Arthritis)

Perceived dyscognition reported by patients with fibromyalgia. Study results provide further evidence that perceived dyscognition in fibromyalgia is influenced by various comorbid symptoms. PubMed, Clin Exp Rheumatol, 02/26/2016. (Also see Fibromyalgia)

Non–stroke Central Neurologic Manifestations in Antiphospholipid Syndrome. Thrombotic manifestations of APS are well known, and various non–stroke neuro–psychiatric manifestations have also been consistently described, but their place in APS remains unclear. PubMed, Curr Rheumatol Rep, 2016 Feb;18(2):11. (Also see Antiphospholipid Syndrome)

Effectiveness of ultrasound treatment applied with exercise therapy on patients with ankylosing spondylitis: a double–blind, randomized, placebo–controlled trial. The study showed that ultrasound treatment increases the effect of exercise in patients with ankylosing spondylitis. PubMed, Rheumatol Int, 02/29/2016. (Also see Ankylosing Spondylitis)

Go to Autoimmune News: March 2016

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