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January 2017 Autoimmune News

Current status of the influence of osteoporosis on periodontology and implant dentistry. The impact of osteoporosis on the periodontal and peri–implant tissues was reviewed to emphasize the importance of oral hygiene measures, and the combined medical/dental assessment when osteoporotic patients are in need of dentoalveolar surgical procedures. PubMed, Curr Opin Endocrinol Diabetes Obes, 2016 Dec;23(6):435-439. (Also see Osteoporosis and Dental Implants)

The role of ultrasound in diagnosing rheumatoid arthritis, what do we know? An updated review. The use of musculoskeletal ultrasound adds value in diagnosing early RA, especially in seronegative arthritis. PubMed, Rheumatol Int, 11/01/2016. (Also see Diagnosis of Rheumatoid Arthritis)

Adrenal crisis while on high-dose steroid treatment: what rheumatologist should consider? We present a patient who developed adrenal crisis while receiving high–dose methylprednisolone treatment due to retroperitoneal fibrosis. PubMed, Rheumatol Int, 11/01/2016. (Also see Glucocorticoids, Steroids (Prednisone) Warnings)

Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases. The present study extends the knowledge of anti–CarP antibodies, confirming previous data on the diagnostic accuracy of anti–CarP in RA in a large cohort of Italian patients. BioMed Central, Arthritis Research & Therapy, 11/25/2016. (Also see Causes of Rheumatoid Arthritis)

Serum 25–OH vitamin D level in treatment–naïve systemic lupus erythematosus (SLE) patients: Relation to disease activity, IL-23 and IL-17. Hypovitaminosis D contributes to ANA antibody production and is associated with high serum levels of IL-23 and IL-17 and may trigger the inflammatory process in SLE. Lupus, 12/07/2016. (Also see Research on Systemic Lupus Erythematosus and Interleukins)

Evaluation of polymorphic variants in apoptotic genes and their role in susceptibility and clinical progression to systemic lupus erythematosus. Our data support a role for apoptosis in SLE susceptibility. PubMed, Lupus, 11/30/2016. (Also see Causes of Lupus)

Enhanced liver fibrosis test (ELF) in psoriasis (PSO), psoriatic arthritis (PsA) and rheumatoid arthritis (RA) patients: a cross–sectional comparison with procollagen–3 N–terminal peptide (P3NP). ELF may be superior to P3NP alone but further research should be done to validated ELF test susceptible for developing liver fibrosis for PSO, PSA and RA. PubMed, Br J Dermatol, 12/07/2016. (Also see Psoriasis and Psoriatic Arthritis)

Bone mineral density (BMD) is decreased in fibromyalgia syndrome (FMS): a systematic review and meta–analysis. In this meta–analysis, we observe that BMD at lumbar spine is decreased in FMS compared with normal individuals. PubMed, Rheumatol Int, 12/05/2016. (Also see Fibromyalgia and Osteoporosis)

Management of psoriatic arthritis in 2016: a comparison of EULAR and GRAPPA recommendations. In this Perspectives article, we address the similarities and differences between these two sets of recommendations and the implications for patient management. PubMed, Nat Rev Rheumatol, 2016 Dec;12(12):743-750. (Also see Psoriasis and Psoriatic Arthritis)

Illness perceptions and burden of disease in fibromyalgia. Long–term prospective studies should be conducted to improve the understanding of the course of illness and to determine whether early diagnosis and intervention can reduce the severity and duration of symptoms. PubMed, Expert Rev Pharmacoecon Outcomes Res, 12/07/2016. (Also see Fibromyalgia)

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