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October 2017 Autoimmune News

Mannose–binding lectin (MBL) deficiency and tuberculosis infection in patients with ankylosing spondylitis (AS). We found a significant association between MBL deficiency and higher risk of tuberculosis and urinary tract infection in patients with AS. PubMed, Clin Rheumatol, 09/06/2017. (Also see Ankylosing Spondylitis and Extrapulmonary Tuberculosis)

Uric acid in major depressive and anxiety disorders. This large scale study suggests the involvement of decreased antioxidant status in affective disorders, and points to their potential as an avenue for treatment. Journal of Affective Disorders, 09/08/2017. (Also see Depression and Anxiety and Attitude)

Patients with fibromyalgia (FM) rarely fulfil classification criteria for axial spondyloarthritis (axSpA). FM patients only rarely fulfil classification criteria for axSpA but some axSpA patients also fulfil FM criteria and assessment instruments evaluated in axSpA are not disease–specific. Rheumatology, 09/08/2017. (Also see Fibromyalgia)

Association between serum vitamin D levels and neuropathic pain (NP) in rheumatoid arthritis (RA) patients: A cross–sectional study. Although further research is needed to clarify the association between serum vitamin D levels and NP, our study raises awareness of the need to screen for vitamin D deficiency in RA patients with NP. PubMed, Int J Rheum Dis, 08/31/2017. (Also see Symptoms and Complications of Rheumatoid Arthritis and Vitamin D Deficiency)

Antibodies to aquaporins (AQPs) are frequent in patients with primary Sjögren’s syndrome (SS). Antibodies to AQPs (especially to AQP8 and AQP9) are frequent in SS patients and the likely important role of AQPs in salivary gland secretions justifies further research. Rheumatology, 08/31/2017. (Also see Diagnosis of Sjögren's Syndrome)

Effectiveness of exercise programs in ankylosing spondylitis (AS): A meta–analysis of randomized controlled trials. Despite the small number of patients and the heterogeneity of exercise programs in this meta–analysis, its results support the potential of exercise programs to improve disease activity and body function in AS. PubMed, Arch Phys Med Rehabil, 08/28/2017. (Also see Ankylosing Spondylitis)

The Birmingham Vasculitis Activity Score (BVAS) is an independent predictor of cardiovascular events and cardiovascular disease–related mortality in patients with ANCA–associated vasculitis (AAV). Besides the traditional risk factors, BVAS at presentation was an independent predictor of cardiovascular events and cardiovascular diseases–related mortality in patients with AAV. Seminars in Arthritis and Rheumatism, 09/07/2017. (Also see Vasculitis)

Cardiometabolic Disorders in Psoriatic Disease (PsD). These findings highlight the importance of controlling disease activity as potential target that could lead to reduced cardiovascular risk in patients with PsD. PubMed, Curr Rheumatol Rep, 2017 Aug 26;19(10):63. (Also see Psoriasis and Psoriatic Arthritis and Cardiac (Heart) Involvement)

Discrepancy between subjective and objective measures of cognitive impairment in patients with rheumatoid arthritis. The findings emphasize the gap between subjective and objective measures of cognitive impairment and the importance of considering psychological factors within the context of cognitive complaints in clinical settings. PubMed, Rheumatol Int, 09/04/2017. (Also see Symptoms and Complications of Rheumatoid Arthritis)

Cytokine signature associated with disease severity in chronic fatigue syndrome patients (CFS). The physicians explored the role of cytokine in CFS and they explained that most of the cytokines were proinflammatory and probably contributed to many of the symptoms of CFS. PubMed, Proc Natl Acad Sci U S A, 2017 Aug 22;114(34):E7150-E7158. (Also see Chronic Fatigue Syndrome and Cytokines)

Go to Autoimmune News: September 2017

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