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August 2018 Autoimmune News

Drug Utilization Patterns and Adherence in Patients on Systemic Medications for the Treatment of Psoriasis: A Retrospective Comparative Cohort Study. We report greater adherence in new users of biologics when compared to methotrexate. PubMed, J Am Acad Dermatol, 07/04/2018. (Also see Psoriasis and Psoriatic Arthritis and Biologic Agents)

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment. This study supports reports highlighting the therapeutic potential of curcumin in psoriasis by providing insight into its immunological effects. PubMed, Sci Rep, 2018 Jul 6;8(1):10287. (Also see Psoriasis and Psoriatic Arthritis)

The effect of depressive symptoms on cognition in patients with fibromyalgia (FM). FM patients show a cluster of cognitive impairment in the attentional and executive domains; some of the symptoms could be explained by depression, while others seem to depend on fibromyalgia. PubMed, PLoS One, 2018 Jul 5;13(7):e0200057. (Also see Fibromyalgia and Depression)

Paresthesia frequency in fibromyalgia and its effects on personality traits. These results suggest that psychological distress associated with high harm avoidance and low self–directedness scores are more prominent in fibromyalgia patients and especially of those who have paresthesia. PubMed, Int J Rheum Dis, 2018 Jul;21(7):1343-1349. (Also see Fibromyalgia)

Predictors of Treatment Response in Rheumatoid Arthritis. This review article discusses the approaches used to identify theranostic biomarkers and to present an overview of currently available biomarkers and of their performance. PubMed, Joint Bone Spine, 07/04/2018. (Also see Treatments for Rheumatoid Arthritis)

High prevalence of widespread pain (WP) in women with early rheumatoid arthritis (RA). A significant group of women with early RA experience WP with a high DAS28 and increased pain intensity level. PubMed, Scand J Rheumatol, 2018 Jul 5:1-8. (Also see Symptoms and Complications of Rheumatoid Arthritis)

Tetraspanin CD82 affects migration, attachment and invasion of rheumatoid arthritis synovial fibroblasts (RASF). CD82 could contribute to RASF migration to sites of inflammation and tissue damage, where CD82 keeps aggressive RASF on site. PubMed, Ann Rheum Dis, 07/06/2018. (Also see Causes of Rheumatoid Arthritis)

Prevalence of overlap of antineutrophil cytoplasmic antibody associated vasculitis (AAV) with systemic autoimmune diseases: an unrecognized example of poliautoimmunity. The most common AAV phenotype was renal–limited vasculitis, and the most frequent overlap disease was rheumatoid arthritis. PubMed, Clin Rheumatol, 07/14/2018. (Also see Vasculitis and Rheumatoid Arthritis in Overlap)

Serum–soluble CXCL16 in juvenile systemic lupus erythematosus (jSLE): a promising predictor of disease severity and lupus nephritis. Serum sCXCL16 might play a role in inflammatory pathogenesis of jSLE particularly in periods of disease activity. PubMed, Clin Rheumatol, 07/13/2018. (Also see Pediatric Lupus)

Depression and anxiety in systemic lupus erythematosus: The crosstalk between immunological, clinical, and psychosocial factors. Despite also suffering from the pain and disability that accompanies chronic autoimmune disease, the rheumatoid arthritis patients had less anxiety and better relationship scores. PubMed, Medicine (Baltimore). 2018 Jul;97(28):e11376. (Also see Depression and Symptoms and Complications of Rheumatoid Arthritis)

Go to Autoimmune News: July 2018

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