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February 2019 Autoimmune News

Eosinophilic fasciitis associated with myositis: Report of four cases and review of the literature. We describe four patients who developed eosinophilic fasciitis, three of whom developed eosinophilic fasciitis with myositis. PubMed, Australas J Dermatol, 12/27/2018. (Also see Eosinophilic Fasciitis and Myopathy and Myositis)

Clinical Phenotype of a First Unprovoked Acute Pulmonary Embolism (PE) Associated with Antiphospholipid Antibody Syndrome (APS). Patients with first unprovoked PE with hemoptysis and have a low pulmonary embolism severity index, should be suspected of having APS, and undergo laboratory testing for positive antiphospholipid antibodies. PubMed, Tuberc Respir Dis (Seoul), 2019 Jan;82(1):53-61. (Also see Antiphospholipid Syndrome)

Identification of Novel Autoantibodies Associated with Psoriatic Arthritis. Our findings suggest that these autoantibodies may be useful biomarkers and indicative of therapeutic targets of psoriasis and psoriatic arthritis. PubMed, Arthritis Rheumatol, 01/07/2019. (Also see Psoriasis and Psoriatic Arthritis)

High Burden of Sexual Dysfunction in Female Patients (FSD) with Rheumatoid Arthritis (RA): Results of a Cross–sectional Study. FSD apparently is highly prevalent in female patients with RA, affects all subdomains of sexual function, and is most likely underestimated in daily clinical practice. PubMed, J Rheumatol, 2019 Jan;46(1):19-26. (Also see Symptoms and Complications of Rheumatoid Arthritis and Female Sexual Dysfunction)

Deltex1 (DTX1) suppresses T cell function and is a biomarker for diagnosis and disease activity of systemic lupus erythematosus (SLE). DTX1 expression in the peripheral blood mononuclear cells was significantly lower in SLE patients and had an inverse correlation with disease activity, indicating that the DTX1 level may be a good disease marker of SLE. PubMed, Rheumatology (Oxford), 01/09/2019. (Also see Diagnosis of Lupus and B Cells and T Cells)

Association of patterns of moderate–to–vigorous physical activity (MVPA) bouts with pain, physical fatigue and disease severity in women with fibromyalgia: the al–√Āndalus project. The results suggest that longer bouts of continuous MVPA are associated with better symptoms profile in this population, which needs to be corroborated in longitudinal research. PubMed, Arch Phys Med Rehabil, 01/05/2019. (Also see Treatments for Fibromyalgia)

The role of human herpes virus-6 (HHV-6) and human herpes virus-7 (HHV-7) infections in the development of fibromyalgia. No difference was found between detection frequency of persistent HHV-6 and HHV-7 infection between FM patients and the control group. PubMed, J Neurovirol, 01/07/2019. (Also see Fibromyalgia)

Factors associated with receiving bone mineral density (BMD) screening among people with multiple sclerosis (MS). Factors known to be associated with low BMD were associated with BMD screening in people with MS, but a clinically meaningful proportion of individuals with MS who have low bone mass may be missed. PubMed, Mult Scler Relat Disord, 2019 Jan 8;28:305-308. (Also see Multiple Sclerosis and Osteoporosis)

Prevalence of fatigue and its association with clinical features in progressive and non–progressive forms of Multiple Sclerosis. Fatigue was more prevalent amongst participants with progressive MS and higher fatigue severity and impact were associated with greater physical, cognitive, and psychological impairment. PubMed, Mult Scler Relat Disord, 2019 Jan 3;28:276-282. (Also see Multiple Sclerosis and Fatigue)

The role of self–efficacy and locus of control in asthma–related needs and outcomes: a cross–sectional study. Our study provides novel evidence on psychological resources among patients with asthma, which are associated with improved asthma outcomes. PubMed, J Asthma, 2019 Jan 11:1-9. (Also see Asthma)

Go to Autoimmune News: January 2019

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