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Scleroderma Newsroom
ISN News Manager: Jo Frowde
Media Stories
Autoimmune Archive
We maintain news archives for the most recent 3 years.
2020: Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2021 - 2020 - 2019 - 2018

August 2020 Autoimmune News

Comparison of Clinical Features and Outcomes Between Patients With Early and Delayed Lupus Nephritis Clinical outcomes of early and delayed lupus nephritis are not significantly different. PubMed, BMC Nephrol, 2020 Jul 7;21(1):258. (Also see Symptoms and Complications of Lupus)

Effect of Methotrexate Use on the Development of Type 2 Diabetes in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis. Rheumatoid arthritis patients on methotrexate treatment had a lower risk of developing type 2 diabetes compared to rheumatoid arthritis patients not exposed to methotrexate. PubMed, PLoS One, 2020 Jul 6;15(7):e0235637. (Also see Symptoms and Complications of Rheumatoid Arthritis and Immunosuppressants)

Left Ventricular (LV) Systolic Function in Patients With Systemic Lupus Erythematosus (SLE) and Its Association With Cardiovascular Events. In patients with SLE, LV systolic function as measured by LV global longitudinal strain is significantly impaired and associated with cardiovascular events. PubMed, J Am Soc Echocardiogr, 2020 Jul 1;S0894-7317(20)30230-3. (Also see Symptoms and Complications of Lupus)

miR-183-3p Suppresses Proliferation and Migration of Keratinocyte (HaCaT) in Psoriasis by Inhibiting GAB1. MiR-183-3p exhibited inhibition property in the proliferation and migration of HaCaT cells via down-regulation of GAB1, suggesting the potential therapeutic strategy for psoriasis. PubMed, Hereditas, 2020 Jul 10;157(1):28. (Also see Psoriasis and Psoriatic Arthritis)

Metabolic Syndrome and Female Gender, but Not Methotrexate, Are the Important Associations of Significant Liver Fibrosis in Patients With Moderate-To-Severe Psoriasis as Detected by Transient Elastography. Metabolic syndrome and female sex are associated with the development of significant liver fibrosis in patients with psoriasis. PubMed, Indian J Dermatol Venereol Leprol, 07/08/2020. (Also see Psoriasis and Psoriatic Arthritis)

Distinct Phenotypes of Islet Antigen-specific CD4+ T Cells Among the Three Subtypes of Type 1 Diabetes. The phenotypes of islet antigen-specific CD4+ T cells differed among the three T1D subtypes. PubMed, J Clin Endocrinol Metab, 07/11/2020. (Also see Research on Diabetes)

Frequency of Reduced Left Ventricular (LV) Contractile Efficiency and Discoordinated Myocardial Relaxation in Patients Aged 16 to 21 Years With Type 1 Diabetes Mellitus (DM). Our results suggest that adolescents with DM have LV systolic and diastolic discoordination, providing early evidence of cardiomyopathy despite their young age. PubMed, Am J Cardiol, 2020 Aug 1;128:45-53. (Also see Symptoms and Complications of Diabetes)

Enteroviruses and Type 1 Diabetes (T1D): Is It the Virus, the Genes or Both Which Cause T1D? This review discusses previously identified virus-associated genetics and pathways of β-cell destruction. PubMed, Microorganisms, 2020 Jul 8;8(7):E1017. (Also see Causes of Diabetes)

Clinical presentation and diagnosis of multiple sclerosis. New diagnostic criteria have been developed to allow an earlier diagnosis and thus access to effective disease modifying treatments. PubMed, Clin Med (Lond), 2020 Jul;20(4):380-383. (Also see Multiple Sclerosis)

Impact of intrathecal IgG synthesis on neurological disability in patients with multiple sclerosis. IgG levels in CSF at MS diagnosis are significantly correlated with the level of neurological disability independent of the relapse frequency. PubMed, Mult Scler Relat Disord, 2020 Jul 7;45:102382. (Also see Multiple Sclerosis)

Go to Autoimmune News: July 2020

SCLERO.ORG was the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses from 1998 to 2021. It was a grassroots movement from the original Scleroderma from A to Z web site, which was founded by Shelley Ensz. We were a 501(c)(3) U.S.-based public charitable foundation. We closed this web site and our nonprofit agency in April 2021.

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