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Autoimmune Archive
We maintain news archives for the most recent 3 years.
2021: Jan Feb
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February 2021 Autoimmune News

The influence of obesity on hydroxychloroquine (HCQ) blood levels in lupus nephritis patients. It was advised to consider the use of 2016-AAO dose of HCQ as per the ideal body weight for this group of patients. PubMed, Lupus, 2021 Jan 5;961203320985214. (Also see Symptoms and Complications of Lupus and DMARDs)

A trial of antithrombotic therapy in patients with refractory migraine and antiphospholipid antibodies: A retrospective study of 75 patients. There was a high rate of symptomatic response to antithrombotic therapy in this context. PubMed, Lupus, 2021 Jan 5;961203320983913. (Also see Antiphospholipid Syndrome)

Association of Therapies With Reduced Pain and Improved Quality of Life in Patients With Fibromyalgia: A Systematic Review and Meta-analysis. This systematic review and meta–analysis suggests that most of the currently available therapies for the management of fibromyalgia are not supported by high–quality evidence. PubMed, JAMA Intern Med, 2021 Jan 1;181(1):104-112. (Also see Fibromyalgia)

Significance of PR3–ANCA positivity in eosinophilic granulomatosis with polyangiitis (EGPA) (Churg-Strauss). This suggests that PR3–ANCA EGPA could be a particular form of PR3–ANCA–associated vasculitis. PubMed, Rheumatology (Oxford), 2020 Dec 21;keaa805. (Also see Granulomatosis with Polyangiitis)

Elevated carcinoembryonic antigen predicts rapidly progressive interstitial lung disease (RP-ILD) in clinically amyopathic dermatomyositis (CADM). An elevated serum CEA level is common in patients with CADM, and a higher serum carcinoembryonic antigen level is a powerful indicator of RP-ILD and poor prognosis in those patients. PubMed, Rheumatology (Oxford), 2021 Jan 4;keaa819. (Also see Dermatomyositis and Polymyositis)

Association of cardiovascular disease (CVD) and traditional cardiovascular (CV) risk factors with the incidence of dementia among patients with rheumatoid arthritis (RA). Patients with RA with both CVD and CV risk factors alone are at an increased risk for dementia compared to those with neither CVD nor CV risk factors. Seminars in Arthritis and Rheumatism, 01/05/2021. (Also see Symptoms and Complications of Rheumatoid Arthritis)

Beta–2–glycoprotein–I IgA antibodies predict coronary plaque progression in rheumatoid arthritis. Anti-β2GPI IgA addition to clinical risk models improved prediction accuracy of coronary artery calcium, plaque progression and transition to extensive/obstructive disease. Seminars in Arthritis and Rheumatism, 12/17/2020. (Also see Symptoms and Complications of Rheumatoid Arthritis and Antibodies)

Role of joint damage, malalignment and inflammation in articular tenderness in rheumatoid arthritis, psoriatic arthritis and osteoarthritis. While tenderness in early arthritis may be more related to inflammation, established disease is better explained by joint damage and malalignment. PubMed, Ann Rheum Dis, 2021 Jan 12;annrheumdis-2020-218744. (Also see Symptoms and Complications of Rheumatoid Arthritis and Psoriasis and Psoriatic Arthritis)

Risk factors associated with adverse pregnancy outcomes (APOs) in patients with new–onset systemic lupus erythematosus (SLE) during pregnancy. New onset SLE during pregnancy increased the risk for multiple APOs. PubMed, Lupus, 2021 Jan 6;961203320980531. (Also see Symptoms and Complications of Lupus and Pregnancy and Autoimmunity)

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Major Impact on Lives of Both Patients and Family Members. This study identifies the major impact that having an adult family member with ME/CFS has on the lives of partners and of other family members. PubMed, Medicina (Kaunas), 2021 Jan 7;57(1):E43. (Also see Chronic Fatigue Syndrome)

Go to Autoimmune News: January 2021

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