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Treatments for Diabetes

Janey WillisHello, I am Janey Willis, ISN Guide to Diabetes. Type 1 Diabetes is an autoimmune disease, and Type 2 Diabetes is caused by risk factors such as lifestyle, ethnicity, age, and pregnancy. The majority of diabetics have Type 2. See Disclaimer.

Overview of Treatments
Treatments for Complications
Hormones
Insulin
Managing Diabetes
Pancreas and Islet Transplants
Stem Cell Transplant

Overview of Treatments for Diabetes

Treatment for Diabetes KaleidoscopeAll people with Type 1 Diabetes need to take insulin because their bodies do not make enough of it. Managing diabetes with diet and exercise is also important. In some cases, pancreas transplants or islet transplantation are considered to control one's diabetes. (Also see Autoimmune Diseases and Overview of Diabetes)

Treatments. This resource is designed to be used with forms that you can print out and personalize to meet your individual needs. National Diabetes Information Clearinghouse.

Treatments for Complications of Diabetes

Hydrogen sulfide (H2S) improves wound healing via restoration of endothelial progenitor cell (EPC) functions and activation of angiopoietin-1 (ANG–1) in type 2 diabetes. H2S improves wound healing by restoration of EPC functions and activation of Ang–1 in type 2 diabetic mice. PubMed, Diabetes, 2014 May;63(5):1763-78.

Hormones

Vitamin D fights cancers and diabetes, is the pivotal feedstock for a hormone that protects muscle, and inhibits autoimmune disorders from multiple sclerosis and lupus to inflammatory bowel disease. Expired article from Science News Online [2005]. (Also see Causes of Scleroderma: Vitamin D Deficiency)

Insulin

Long-Term Efficacy and Safety of Sensor Augmented Insulin Pump (SAP) Therapy with Low-Glucose Suspend (LGS) Feature in Patients with Type 1 Diabetes (T1D). SAP+LGS therapy in T1D patients with hypoglycemia led to a significant and sustained decrease in glycated hemoglobin during long periods of follow-up, as well as a significant reduction in severe hypoglycemia and hypoglycemia unawareness. PubMed, Diabetes Technol Ther, 12/21/2016.

Managing Diabetes

Diabetes: How lifestyle and daily routine affect blood sugar. You can keep your blood sugar within target range and prevent diabetes complications by knowing what makes your blood sugar rise and fall. Take a look at the day-to-day factors that can cause your blood sugar to rise and fall. Then find out how to cope with them. MayoClinic.

Pancreas and Islet Transplants

Long–term diabetes complications after pancreas transplantation. In patients with type 1 diabetes, pancreas transplantation may improve cardiac outcomes and ameliorate diabetic lesions in the kidney transplant. PubMed, Curr Opin Organ Transplant, 06/08/2017.

Pancreas Islet Transplantation for Patients With Type 1 Diabetes Mellitus: A Clinical Evidence Review. For patients with type 1 diabetes with difficult-to-control blood glucose levels, islet transplantation may be a beneficial ß-cell replacement therapy to improve glycemic control and secondary complications of diabetes. PubMed, Ont Health Technol Assess Ser, 2015 Sep 1;15(16):1-84.

Transplantation of Encapsulated Pancreatic Islets as a Treatment for Patients with Type 1 Diabetes Mellitus. Under active collaboration between research facilities, the end goal of providing islet encapsulation as a viable cure for patients with T1DM without immunosuppressant would be achievable. Hindawi, 01/13/2014.

Stem Cell Transplants

Stem Cells and Diabetes. Despite progress in understanding the underlying disease mechanisms for diabetes, there is still a paucity of effective therapies. NIH.

Transplantation of mesenchymal stem cells (MSCs) improves type 1 diabetes mellitus. Intrapancreatic transplantation of MSCs triggers a series of molecular and cellular events, including differentiation towards the pancreas directly and the provision of a niche to start endogenous pancreatic regeneration. PubMed, Cell Tissue Res, 12/09/2015.

Go to Research on Diabetes
 
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