Hello, I am Janey Willis, ISN Guide to Diabetes. Type 1 Diabetes is an autoimmune disease, and Type 2 Diabetes is caused by risk factors such as lifestyle, ethnicity, age, and pregnancy. The majority of diabetics have Type 2. See Disclaimer.
|Overview of Treatments
Treatments for Complications
Pancreas and Islet Transplants
Stem Cell Transplant
All people with Type 1 Diabetes need to take insulin because their bodies do not make enough of it. Managing diabetes with diet and exercise is also important. In some cases, pancreas transplants or islet transplantation are considered to control one's diabetes. (Also see Autoimmune Diseases and Overview of Diabetes)
Treatments. This resource is designed to be used with forms that you can print out and personalize to meet your individual needs. National Diabetes Information Clearinghouse.
Autologous Bone Marrow–Derived Stem Cells (BMC) for Treating Diabetic Neuropathy in Metabolic Syndrome. In this review, we discuss the clinical practice in diabetic neuropathy and the therapeutic effect of BMC. PubMed, Biomed Res Int, 2017;2017:8945310.
Vitamin D fights cancers and diabetes, is the pivotal feedstock for a hormone that protects muscle, and inhibits autoimmune disorders from multiple sclerosis and lupus to inflammatory bowel disease. Expired article from Science News Online . (Also see Causes of Scleroderma: Vitamin D Deficiency)
Long-Term Efficacy and Safety of Sensor Augmented Insulin Pump (SAP) Therapy with Low-Glucose Suspend (LGS) Feature in Patients with Type 1 Diabetes (T1D). SAP+LGS therapy in T1D patients with hypoglycemia led to a significant and sustained decrease in glycated hemoglobin during long periods of follow-up, as well as a significant reduction in severe hypoglycemia and hypoglycemia unawareness. PubMed, Diabetes Technol Ther, 12/21/2016.
Diabetes: How lifestyle and daily routine affect blood sugar. You can keep your blood sugar within target range and prevent diabetes complications by knowing what makes your blood sugar rise and fall. Take a look at the day-to-day factors that can cause your blood sugar to rise and fall. Then find out how to cope with them. MayoClinic.
Under pressure in diabetes, Novo Nordisk steps up focus on obesity drugs. The world’s largest maker of diabetes drugs said it would aim to develop medicines that treat obesity – a major cause of diabetes – at least as effectively as surgery. Reuters Health, 11/21/2017.
How Weight Loss Can Reverse Type 2 Diabetes. An analysis published in The BMJ aims to let doctors and the public in on a little–known secret: Type 2 diabetes, in many cases, is curable. Time Healthland, 09/13/2017.
Beta–cell therapies for type 1 diabetes: Transplants and bionics. This article reviews the current state of beta–cell replacement through transplant of the whole pancreas or of islet cells. PubMed, Cleve Clin J Med, 2018 Dec;85(12):931-937.
Long–term diabetes complications after pancreas transplantation. In patients with type 1 diabetes, pancreas transplantation may improve cardiac outcomes and ameliorate diabetic lesions in the kidney transplant. PubMed, Curr Opin Organ Transplant, 06/08/2017.
Stem Cells and Diabetes. Despite progress in understanding the underlying disease mechanisms for diabetes, there is still a paucity of effective therapies. NIH.
Doctors discover new method to heal painful diabetic ulcers using a jab of 'muffin top' fat. Doctors have discovered an ingenious use for the excess fat — they are using it in injections for painful foot ulcers that are difficult to treat. Mail Online, 12/02/2017. (Also see Treatments for Digital Ulcers)
Transplantation of mesenchymal stem cells (MSCs) improves type 1 diabetes mellitus. Intrapancreatic transplantation of MSCs triggers a series of molecular and cellular events, including differentiation towards the pancreas directly and the provision of a niche to start endogenous pancreatic regeneration. PubMed, Cell Tissue Res, 2016 May;364(2):345-55.
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