Pediatric Lupus

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Quality of Life

Overview of Pediatric Lupus

Pediatric Lupus refers to any form of lupus that onsets during childhoood. It generally begins with vague symptoms like weakness, joint pain, weight loss, fatigue and/or rashes. After a few months, more serious symptoms may set in.

Lupus in childhood tends to be a bit more aggressive and less responsive to treatment than when it onsets in adulthood. (Also see Autoimmune Diseases, Overview of Lupus and Lupus Treatments)

Differences in disease phenotype and severity in systemic lupus erythematosus (SLE) across age groups. Direct comparison of juvenile–onset SLE (JSLE) with adult–onset SLE suggest an aggressive phenotype of disease with a worse outcome in patients with JSLE and emphasizes the importance of careful follow–up in this population. PubMed, Lupus, 05/04/2016.

Diagnosis of Pediatric Lupus

Serum–soluble CXCL16 in juvenile systemic lupus erythematosus (jSLE): a promising predictor of disease severity and lupus nephritis. Serum sCXCL16 might play a role in inflammatory pathogenesis of jSLE particularly in periods of disease activity. PubMed, Clin Rheumatol, 07/13/2018.

Systemic Lupus Erythematosus in Children and Teens. Lupus is a disease that is diagnosed by a combination of at least four physical symptoms and/or blood test abnormalities. American College of Rheumatology.

Symptoms of Pediatric Lupus

Common symptoms of juvenile onset systemic lupus erythematosus may include arthritis, rashes, blood disorders, mouth or nose sores, seizures, fever, fatigue, and heart, lung, or kidney problems.

Quality of Life with Pediatric Lupus

Research May Help Clinicians Improve Quality of Life among Children with Lupus. Using the PROMIS questionnaire in children and adolescents with lupus allows clinicians to better design treatment plans for their patients, improve communication and overall management of disease and ultimately have a positive impact on a patient's quality of life. Lupus Foundation of America.

Go to Symptoms of Lupus

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