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Pediatric Lupus

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview
Diagnosis
Symptoms

Overview of Pediatric Lupus

Pediatric Lupus refers to any form of lupus that onsets during childhoood. It generally begins with vague symptoms like weakness, joint pain, weight loss, fatigue and/or rashes. After a few months, more serious symptoms may set in.

Lupus in childhood tends to be a bit more aggressive and less responsive to treatment than when it onsets in adulthood. (Also see Autoimmune Diseases, Overview of Lupus and Lupus Treatments)

Diagnosis of Pediatric Lupus

Cytokines, 25-OH vit D and disease activity in patients with juvenile-onset systemic lupus erythematosus (SLE). IFN-γ and IL-17 were significantly higher in JO-SLE patients, while 25-OH Vit D was significantly lower compared to controls. PubMed, Lupus, 2020 Nov 12;961203320973068. (Also see Cytokines)

Serum–soluble CXCL16 in juvenile systemic lupus erythematosus (jSLE): a promising predictor of disease severity and lupus nephritis. Serum sCXCL16 might play a role in inflammatory pathogenesis of jSLE particularly in periods of disease activity. PubMed, Clin Rheumatol, 07/13/2018.

Systemic Lupus Erythematosus in Children and Teens. Lupus is a disease that is diagnosed by a combination of at least four physical symptoms and/or blood test abnormalities. American College of Rheumatology.

Symptoms of Pediatric Lupus

Common symptoms of juvenile onset systemic lupus erythematosus may include arthritis, rashes, blood disorders, mouth or nose sores, seizures, fever, fatigue, and heart, lung, or kidney problems.

Go to Symptoms of Lupus
 
 

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