Pediatric Lupus refers to any form of lupus that onsets during childhoood. It generally begins with vague symptoms like weakness, joint pain, weight loss, fatigue and/or rashes. After a few months, more serious symptoms may set in.
Cytokines, 25-OH vit D and disease activity in patients with juvenile-onset systemic lupus erythematosus (SLE). IFN-γ and IL-17 were significantly higher in JO-SLE patients, while 25-OH Vit D was significantly lower compared to controls. PubMed, Lupus, 2020 Nov 12;961203320973068. (Also see Cytokines)
Serum–soluble CXCL16 in juvenile systemic lupus erythematosus (jSLE): a promising predictor of disease severity and lupus nephritis. Serum sCXCL16 might play a role in inflammatory pathogenesis of jSLE particularly in periods of disease activity. PubMed, Clin Rheumatol, 07/13/2018.
Systemic Lupus Erythematosus in Children and Teens. Lupus is a disease that is diagnosed by a combination of at least four physical symptoms and/or blood test abnormalities. American College of Rheumatology.
Common symptoms of juvenile onset systemic lupus erythematosus may include arthritis, rashes, blood disorders, mouth or nose sores, seizures, fever, fatigue, and heart, lung, or kidney problems.
SCLERO.ORG was the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses from 1998 to 2021. It was a grassroots movement from the original Scleroderma from A to Z web site, which was founded by Shelley Ensz. We were a 501(c)(3) U.S.-based public charitable foundation. We closed this web site and our nonprofit agency in April 2021.