Systemic Autoimmune Rheumatic Diseases

Author: Janey Willis. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer


Rheumatic KaleidoscopeSystemic autoimmune rheumatic diseases are different from most autoimmune diseases in that they affect many organs, cells or tissues simultaneously rather than just one. Examples of rheumatic diseases are systemic sclerosis (systemic scleroderma), lupus, rheumatoid arthritis, Sjögren's, dermatomyositis, and polymyositis. Examples of non-rheumatic diseases are diabetes, autoimmune hepatitis, autoimmune thyroid disease, and psoriasis.

The National Data Bank (NDB) for rheumatic diseases: Diagnosis List. If you have been diagnosed with one or more conditions from the following list, you are eligible to participate in NDB research. If you have a diagnosis for a rheumatic disease that you do not see listed, please contact us. The NDB for Rheumatic Disease. (Also see Research Registries)

Symptoms and Complications of Autoimmune Rheumatic Diseases

These 4 changes in your facial skin could signal a serious medical condition. The dark circles around your eyes or nagging acne on your face may be telling you more about your health than you think. Today Health News, 12/09/2017.

Ocular Involvement in Systemic Autoimmune Diseases. The aim of this review is to elucidate to non-ophthalmologists the major ocular complications of rheumatic diseases and their specific management and treatment options. PubMed, Clin Rev Allergy Immunol, 10/22/2015. (Also see Eye Involvement of Rheumatic Diseases)

Depression, anxiety, and quality of life in a large cohort of patients with rheumatic diseases: common, yet undertreated. For the management of depression and anxiety, an increased awareness among physicians dealing with rheumatologic patients is warranted in order to integrate detection and effective treatment of anxiety and depression into the routine clinical practice. PubMed, Clin Rheumatol, 2014 May 25. (Also see Depression)

Eye Involvement. ISN

Symptoms and Complications of Scleroderma. ISN.

Symptoms and Complications of Lupus. ISN.

Symptoms and Complications of Dermatomyositis and Polymyositis. ISN.

Symptoms and Complications of Sjögren's. ISN.

Symptoms and Complications of Rheumatoid Arthritis. ISN.


Human microbiome, infections, and rheumatic disease. It is now clear that there is direct and indirect cross talk between the microbiome and host immune responses. PubMed, Clin Rheumatol, 2017 Dec;36(12):2645-2653.

Enzyme identified as a major culprit of autoimmune diseases. Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report. Science Daily, 10/27/2015.


Diagnosis of Scleroderma. ISN.

Diagnosisof Lupus. ISN.

Diagnosisof Dermatomyositis and Polymyositis. ISN.

Diagnosisof Sjögren's. ISN.

Diagnosisof Rheumatoid Arthritis. ISN.


Autoantibodies in Systemic Rheumatic Diseases. Specialized blood tests such as antinuclear antibody (ANA) tests are sometimes useful in the diagnosis or categorization of both localized and systemic scleroderma, as well as overlapping or other autoimmune diseases. ISN.


Treatments for Rheumatic Diseases. ISN.

Go to Rheumatoid Arthritis

Giving Assistant
United Way of Central New Mexico
United Way of Snohomish County
See ISN News for recent donors, including Pam Hop, Margaret Roof, Winifred Schillberg, Arnold Slotkin, and Juliet Youkhana. Plus donations in honor of Kim Thwaits, and in loving memory of Marta Marx, Jim Miller, and Arlene Marie Petulla.
Click Here to Donate or Shop
or click on the floating green DONATE button.


TOLL FREE HOTLINE, U.S. and Canada: 1-800-564-7099
Ask for our Free Info Packet by email or postal mail!

SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to:

International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA
Email [email protected] to request our Welcome email, or to report bad links or to update this page content. Privacy Policy.

The most important thing in the world to know about scleroderma is!

Donate Now
Copyright 1998-2018, International Scleroderma Network. AKA Scleroderma from A to Z and SCLERO.ORG. All Rights Reserved.