Hashimoto's Thyroiditis or Hypothyroidism

Overview of Hashimoto's
Symptoms of Hashitmoto's
Causes of Hashimoto's
Diagnosis of Hashimoto's
Treatments of Hashimoto's
Cancer and Hashimoto's
Central Nervous System and Dementia with Hashimoto's
Sleep Apnea and Hashimoto's
Thyroid Support


Hashimoto's thyroiditis is an autoimmune disease that causes inflammation of the thyroid gland, causing hypothyroidism (a depletion of thyroid hormone.) It is diagnosed by blood tests for thyroid antibodies, and treated with thyroid replacement medications.

Hashimoto's Thyroiditis. Hashimoto's thyroiditis is the most common cause of hypothyroidism in the United States. Hashimoto's thyroiditis is a condition caused by inflammation of the thyroid gland.

Hashimoto's vs. Hypothyroidism: What's the Difference? Hashimoto's disease is a disease, and hypothyroidism is a condition. Hypothyroidism is most commonly caused by Hashimoto's disease, but the two terms are not interchangeable. Here is more information to help understand the difference. VeryWell.

Hashimoto's thyroiditis (HT): Relative recurrence risk ratio and implications for screening of first degree relatives. Relatives of HT patients have a 9 fold increased risk for developing HT as compared to the general population and the risk of developing HT exceeds that of the general population at 20 years in females and 27 years in males. PubMed, Clin Endocrinol (Oxf), 03/08/2017.


Symptoms of Hashimoto's Thyroiditis. Symptoms may include fatigue, cold sensitivity, constipation, dry skin, puffy face, hoarseness, weight gain, muscle weakness and aches, joint pain, menorrhagia, and depression. Mayo Clinic.


Hashimoto's Thyroiditis Diagnosis. This article covers the 3 most common diagnostic tests that detect this common thyroid disorder: the thyroid-stimulating hormone test, anti-thyroid antibodies tests, and the free T4 hormone test. Endocrineweb.


Hashimoto thyroiditis (HT), anti–thyroid antibodies and systemic lupus erythematosus (SLE). There is a two–fold increased risk of HT in SLE patients, Anti–SM antibodies favor this association and also double antibody positivity. PubMed, Int J Rheum Dis, 05/25/2017. (Also see Antibodies in Lupus)

An unusual association of three autoimmune disorders: celiac disease (CD), systemic lupus erythematosus (SLE) and Hashimoto's thyroiditis. This case is unusual: the rare combination of the three autoimmune diseases, their appearance in a man and the atypical onset of the diseases with psychiatric symptoms likely to be related either to CD or to SLE. PubMed, Auto Immun Highlights, 2016 Dec;7(1):7. (Also see Lupus in Overlap, Celiac Disease and Multiple Autoimmune Syndrome)

The relationship between oxidative stress and autoimmunity in Hashimoto's thyroiditis (HT). The results suggest that oxidative stress increases continuously during the development of subclinical hypothyroidism and overt hypothyroidism in patients with HT. PubMed, Eur J Endocrinol, 2015 Dec;173(6):791-9.

Meta-Analysis of the Association between Vitamin D and Autoimmune Thyroid Disease. Vitamin D deficiency is prevalent in AITD subjects and that these subjects have lower levels of serum 25(OH)D, suggesting that lower serum vitamin D is related to AITD and the deficiency in vitamin D may plays a role in the development of the disease. NCBI, Nutrients, 2015 Apr; 7(4): 2485-2498.

(Case Report) A rare association of localized scleroderma (LS) type morphea, vitiligo, autoimmune hypothyroidism, pneumonitis, autoimmune thrombocytopenic purpura and central nervous system vasculitis. It is likely that localized scleroderma has an autoimmune origin and in this case becomes part of multiple autoimmune syndrome (MAS), which consist of the presence of three or more well-defined autoimmune diseases in a single patient. PubMed, BMC Res Notes. (Also see Causes of Morphea, Vitiligo, Idiopathic Thrombocytopenic Purpura, Vasculitis, and Multiple Autoimmune Syndrome)

Treatments of Hashimoto's Thyroiditis

Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement. The purpose of this task force was to review the goals of levothyroxine therapy, the optimal prescription of conventional levothyroxine therapy, the sources of dissatisfaction with levothyroxine therapy, the evidence on treatment alternatives, and the relevant knowledge gaps. Thyroid, December 2014, 24(12): 1670-1751.

Cancer and Hashimoto's Thyroiditis

Papillary thyroid carcinoma linked to Hashimoto's thyroiditis. Data from a recent meta-analysis demonstrate that papillary thyroid cancer is significantly associated with pathologically confirmed Hashimoto's thyroiditis, despite decades of controversy. Eur J Endocrinol.

Central Nervous System (CNS) and Dementia with Hashimoto's

Hashimoto's encephalopathy presenting with acute confusional state in a patient with hypothyroidism. Hashimoto's encephalopathy is a neurological disorder of unknown etiology associated with thyroid autoimmunity. The disease may present as two types, a sudden vasculitic type or a progressive subacute type associated with cognitive dysfunction, confusion and memory loss. ScienceDirect, Egyptian Pediatric Association Gazette, Volume 63, Issue 2, June 2015, Pages 69-73.


Goiters. The term “goiter” simply refers to the abnormal enlargement of the thyroid gland. Hashimoto's thyroiditis is a more common cause of goiter formation in the US. American Thyroid Association.

Sleep Apnea and Hashimoto's

Hashimoto thyroiditis and obstructive sleep apnea syndrome: is there any relation between them? Five patients with HT showed the characteristics of obstructive sleep apnea syndrome (one severe, one moderate and three mild OSAS), whereas no sleep breathing disturbance was found in the control group. These findings suggest that sleep related breathing problems may develop in the patients with autoimmune thyroiditis even if they are euthyroid. PubMed, Eur J Med Res, [2004] Dec 22;9(12):570-2.

Thyroid Education and Support

How Armour® Thyroid Differs From Synthetic Thyroid Hormone Replacements. Armour Thyroid.

Chronic Fatigue Syndrome and Fibromyalgia. ISN.

Go to Thyroid Personal Stories

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