Dendritic cells are involved in the regulation of the body's immune system response, and are thought to be a key to preventing or treating autoimmune diseases. (Also see: Causes of Scleroderma, What is Scleroderma?, Types of Scleroderma, and Systemic Sclerosis)
Dendritic cells (DC) maintain dermal adipose–derived stromal cells (ADSCs) in skin fibrosis. These findings provide insight into the effects of skin fibrosis on the dermal white adipose tissue ADSCs, identify a DC-ADSC survival axis in fibrotic skin, and suggest an approach for improving mesenchymal stromal cell therapy in scleroderma and other diseases. PubMed, 10/10/2016.
Contribution of Dendritic cells (DCs) to the autoimmune pathology of Systemic Lupus Erythematosus. In this review article the authors discuss the most relevant data relative to the contribution of DCs to the triggering of SLE. PubMed, Immunology, 07/17/2015.
United Way of Central New Mexico
United Way of Snohomish County
See ISN News for recent donors, including Pam Hop, Margaret Roof, Winifred Schillberg, Arnold Slotkin, and Juliet Youkhana. Plus donations in honor of Kim Thwaits, and in loving memory of Marta Marx, Jim Miller, and Arlene Marie Petulla.
Click Here to Donate or Shop
or click on the floating green DONATE sclero.org button.
SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to: