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Cardiac (Heart) Involvement in Systemic Sclerosis (Scleroderma)

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview and Video
Symptoms
Correlation with Other Diseases
Systemic Scleroderma
Complications
Diagnosis
Treatments
Research
Personal Stories

Overview and Video

Scleroderma Heart Involvement Video
Video: Scleroderma Heart Involvement

Presented by Amanda Thorpe
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The systemic forms of scleroderma can cause cardiac (heart) problems. One of the earliest symptoms reported by diffuse systemic scleroderma patients is heart irregularities. Systemic scleroderma can cause arrhythmias, pericardial effusion, and heart failure.

Formation of scar tissue in the heart and lungs has recently been recognized as a general pattern probably contributing to overall fatigue. It is very important for people with diffuse scleroderma to see a listed scleroderma expert and to report any heart-related symptoms if or when they arise. (Also see What is Scleroderma? and Types of Scleroderma, and Scleroderma Experts)

Keeping feelings bottled up could put women at risk of stroke: Study Women who tend to keep quiet about their feelings may be at risk for a stroke and other cardiovascular risks, according to presentation being made at the annual meeting of The North American Menopause Society. GMA Wellness, 09/26/2019.

8 Science-Backed Ways to Prevent Heart Attacks, According to New Guidelines. Experts have issued a new set of guidelines on the best ways to prevent first heart attacks, strokes and heart failure – and for the first time, they focus squarely on the patient. Time Healthland, 03/18/2019.

Workplace bullying and violence tied to higher risk of heart problems. People who are bullied or exposed to violence on the job may be more likely to develop cardiovascular disease than individuals who don’t deal with these challenges at work, a European study suggests. Reuters Health, 11/19/2018.

Poverty tied to worse heart health among U.S. teens. Adolescents from low–income families are more likely than their affluent peers to have risk factors for cardiovascular disease, a U.S. study suggests. Reuters Health, 10/17/2018.

Tooth loss in middle age linked to heart disease. Losing two or more natural teeth in middle age may signal an increased risk for coronary heart disease, a U.S. study suggests. Reuters Health, 04/18/2018. (Also see Periodontal Disease)

Regular exercise may improve odds of surviving a heart attack. Just a few hours a week of moderate exercise may not prevent all heart attacks, but it could make the difference in who survives one, Danish researchers say. Reuters Health, 04/20/2017.

Higher heart risk seen with Abbott dissolving stent after two years: study. New guidelines for blood vessel size and proper implantation techniques put in place for the new Absorb stent since the study began, however, should lead to better results, researchers said. Reuters Health, 03/18/2017.

10 Weird Things That May Affect Your Heart Disease Risk. Research suggests that your cardiovascular health could be influenced by where you live, how many kids you have, and more. Time Health, 02/09/2017.

The Power of Simple Life Changes to Prevent Heart Disease. Lifestyle changes are hugely important not only for those at low risk of heart disease, but for those at high risk and it’s clear that a healthier lifestyle could have huge implications for many, many more people. New York Times, 12/12/2016.

More than half a MILLION heart surgery patients 'exposed to deadly infection from contaminated tools'. More than half a million heart surgery patients may have contracted a deadly infection from contaminated machinery in the operating room. Mail Online, 10/14/2016.

Good Heart Attack Care Could Add a Year to Your Life: Study. Going to the right hospital for heart attack care could add a year to your life, a new study suggests. NBC Health News, 10/05/2016.

Life–saving heart devices often inaccessible in public places. One in five cardiac arrests outside of hospitals occurred near an automated external defibrillator (AED) that was inaccessible at the time, researchers' study found. Reuters Health, 08/19/2016.

Sitting Really Can Kill You, Heart Experts Say. Evidence is building that sitting for too long can cause heart disease and diabetes – even in people who exercise, the American Heart Association said Monday. NBC News, 08/15/2016. (Also see Causes of Diabetes)

Cutting Sugar Rapidly Improves Heart Health Markers. Obese children who cut sugar from their diets saw improvements in markers of heart disease after just nine days, a study in Atherosclerosis found. Time Healthland, 07/19/2016.

Hospitalizations for heart failure spike after major holidays. The number of people admitted to hospitals for heart failure drops on major holidays but then climbs in the days that follow, a new study suggests. Reuters Health, 06/17/2016.

Cardiac (Heart) Symptoms

Cardiac (Heart) Symptoms. Common symptoms of heart failure include breathing difficulties, fatigue and exercise intolerance, and coughing. ISN.

Overview
Heart Symptoms in Women
Chest Pain
Common Symptoms of Heart Failure
Fainting (Syncope)

Correlation Between Cardiac and Other Diseases

Number of potentially fatal heart attacks drops by roughly 20 per cent after the clocks go back, study shows. A study of 460,000 Britons found that even those without family history of heart disease dramatically increased their risk of a heart attack by sacrificing sleep. Mail Online, 10/26/2019.

Effects of autonomic dysfunction (AD) on exercise tolerance in systemic sclerosis (SSc) patients without clinical and instrumental evidence of cardiac and pulmonary involvement. In SSc patients without cardiopulmonary involvement AD is associated with better exercise tolerance and cardiac function during physical effort. PubMed, Clin Exp Rheumatol, 05/04/2018. (Also see Brain Involvement)

Cardiometabolic Disorders in Psoriatic Disease (PsD). These findings highlight the importance of controlling disease activity as potential target that could lead to reduced cardiovascular risk in patients with PsD. PubMed, Curr Rheumatol Rep, 2017 Aug 26;19(10):63. (Also see Psoriasis and Psoriatic Arthritis)

Cardiac Involvement in Granulomatosis with Polyangiitis (GPA) : a magnetic resonance imaging study of 31 consecutive patients. This unique non–invasive technique may provide information with important clinical implications for the accurate early assessment of cardiac lesions in GPA patients and for detecting cumulative, irreversible damage. PubMed, Rheumatology (Oxford), 2017 Jun 1;56(6):947-956 (Also see Granulomatosis with Polyangiitis)

Hot flashes at younger ages may signal higher heart risk later. Women who start having hot flashes in their 40s and early 50s had signs of poorer blood vessel health in a recent study and may be at a higher risk of cardiovascular disease later on, researchers say. Reuters Health, 04/21/2017.

Heart Health Is Linked to Brain Health: Study. Having a healthy heart can help preserve brain processing and cognitive function over time, according to a new study published. Time Healthland, 03/16/2016.

Nocturia in Patients With Sleep-Disordered Breathing (SDB) and Cardiovascular Disease (CVD). Continuous positive airway pressure has the potential to reduce nocturia and risk factors for SDB, which may be beneficial in older men with CVD and obstructive sleep apnea. PubMed, Circ J. (Also see Sleep Apnea)

Myopathies related to systemic sclerosis: a case-control study of associated clinical and immunological features. Heart monitoring of SSc patients with myopathy should be undertaken regularly because of the association of myocardial and skeletal myopathies in such patients. PubMed, Scand J Rheumatol. (Also see Myopathies)

Antiphospholipid Syndrome (APS) and Heart Disease. ISN.

Systemic Scleroderma Heart Involvement

Systemic Scleroderma Cardiac (Heart) Involvement. The systemic forms of scleroderma can cause cardiac (heart) problems. One of the earliest symptoms reported by diffuse systemic scleroderma patients is heart irregularities. ISN.

Overview
Antiphospholipid
Aortic Stiffness
Asymptomatic Pericardial
Cardiac Remodeling
Carotid Artery Disease
Cholesterol
Atherosclerosis
Left Ventricle
Lipoprotein[a], Thrombotic
Mitral/Tricuspid Valve
Myocardial Ischemia
Right Ventricle
Stroke and TIA

Vascular Disease and Systemic Scleroderma. The vascular system is our circulatory system. It consists of all the vessels that carry blood and lymph through the body, to and from organs. Vessels include arteries, veins, and capillaries. Any condition that affects the vascular system, all of in part, is considered a vascular disease. ISN.

Overview
Vascular in Scleroderma
Causes
Types in Scleroderma
In Other CTDs
Biomarkers
Angiogenesis
Hypoxia
VEGF
Personal Stories
Related Information

Complications with Systemic Scleroderma Heart Involvement

Complications with Systemic Scleroderma Cardiac (Heart) Involvement include atrioventricular heart block, cardiogenic shock, myocardial infarction, and skeletal myopathy. ISN.

Overview
Aneurysms
Aortic Valve Insufficiency
Arrhythmia
Atrioventricular Heart Block
Cardiogenic Shock
Cardiac Tamponade
Diastolic Dysfunction
Macrovascular Disease
Myocardial Infarction
Skeletal Myopathy

Diagnosis

Diagnosis of Systemic Scleroderma Cardiac (Heart) Involvement. It is common for patients with systemic scleroderma to develop heart involvement even without any overt cardiac symptoms, so mandatory assessment of systemic scleroderma heart involvement requires a thorough baseline screening and follow-up monitoring. ISN.

Overview
CT Scans
Echocardiography
--ECHO (General)
--Tissue Doppler
Electrocardiogram
Heart Rate
MRI and CV-MRI
Holter Monitoring
Scintigraphy

Treatments

Treatments for Systemic Scleroderma Cardiac (Heart) Involvement include Bosentan, and calcium channel blockers such as nicardipine (Cardene) and nifedipine (Adalat, Procardia). ISN.

Beta Blockers
Bosentan, Tracleer
Combination Therapy
Calcium Channel Blockers
Nicardipine, Nifedipine
Coronary Artery Bypass
Dietary Approaches
Pericarditis Treatments

Research

Research about Systemic Scleroderma Heart Involvement. Topics include antibodies, autoimmunity, case studies, and causes of scleroderma heart involvement. ISN.

Antibodies
Autoimmunity and Heart Disease
Causes of Heart Disease

Personal Stories: Cardiac (Heart) Involvement

Patient and Caregiver Stories: Cardiac (Heart) Involvement. ISN.

Anastasia: Surviving Granddaughter of a Diffuse Scleroderma Patient Traveling to a different hospital finally we heard scleroderma…

Angela S: Overlap Syndrome I am twenty-five years old and I was diagnosed with polymyositis and scleroderma, rheumatoid arthritis, mitral valve prolapse, a heart murmur, and pericarditis…

Angiola: Progressive Systemic Scleroderma (Italy) I would very much like to find other people that find themselves in a similar situation…

Read more stories…

Go to Complications
 

In Loving Memory of Lorraine Wempner, a donation to tackle scleroderma has been made by Paul Wempner. Posted 11/13/2019. (Also see: ISN News)

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