| Overview and Video
Correlation with Other Diseases
The systemic forms of scleroderma can cause cardiac (heart) problems. One of the earliest symptoms reported by diffuse systemic scleroderma patients is heart irregularities. Systemic scleroderma can cause arrhythmias, pericardial effusion, and heart failure.
Formation of scar tissue in the heart and lungs has recently been recognized as a general pattern probably contributing to overall fatigue. It is very important for people with diffuse scleroderma to see a listed scleroderma expert and to report any heart-related symptoms if or when they arise. (Also see What is Scleroderma? and Types of Scleroderma, and Scleroderma Experts)
Progress in Understanding, Diagnosing, and Managing Cardiac Complications of Systemic Sclerosis. Recent application of novel cardiac detection strategies is providing increased insight into the breadth and pathogenesis of cardiac complications of scleroderma. PubMed, Curr Rheumatol Rep, 2019 Dec 7;21(12):68.
Keeping feelings bottled up could put women at risk of stroke: Study Women who tend to keep quiet about their feelings may be at risk for a stroke and other cardiovascular risks, according to presentation being made at the annual meeting of The North American Menopause Society. GMA Wellness, 09/26/2019.
8 Science-Backed Ways to Prevent Heart Attacks, According to New Guidelines. Experts have issued a new set of guidelines on the best ways to prevent first heart attacks, strokes and heart failure – and for the first time, they focus squarely on the patient. Time Healthland, 03/18/2019.
Workplace bullying and violence tied to higher risk of heart problems. People who are bullied or exposed to violence on the job may be more likely to develop cardiovascular disease than individuals who don’t deal with these challenges at work, a European study suggests. Reuters Health, 11/19/2018.
Poverty tied to worse heart health among U.S. teens. Adolescents from low–income families are more likely than their affluent peers to have risk factors for cardiovascular disease, a U.S. study suggests. Reuters Health, 10/17/2018.
Tooth loss in middle age linked to heart disease. Losing two or more natural teeth in middle age may signal an increased risk for coronary heart disease, a U.S. study suggests. Reuters Health, 04/18/2018. (Also see Periodontal Disease)
Regular exercise may improve odds of surviving a heart attack. Just a few hours a week of moderate exercise may not prevent all heart attacks, but it could make the difference in who survives one, Danish researchers say. Reuters Health, 04/20/2017.
Higher heart risk seen with Abbott dissolving stent after two years: study. New guidelines for blood vessel size and proper implantation techniques put in place for the new Absorb stent since the study began, however, should lead to better results, researchers said. Reuters Health, 03/18/2017.
10 Weird Things That May Affect Your Heart Disease Risk. Research suggests that your cardiovascular health could be influenced by where you live, how many kids you have, and more. Time Health, 02/09/2017.
Cardiac (Heart) Symptoms. Common symptoms of heart failure include breathing difficulties, fatigue and exercise intolerance, and coughing. ISN.
Heart Symptoms in Women
|Common Symptoms of Heart Failure
Number of potentially fatal heart attacks drops by roughly 20 per cent after the clocks go back, study shows. A study of 460,000 Britons found that even those without family history of heart disease dramatically increased their risk of a heart attack by sacrificing sleep. Mail Online, 10/26/2019.
Effects of autonomic dysfunction (AD) on exercise tolerance in systemic sclerosis (SSc) patients without clinical and instrumental evidence of cardiac and pulmonary involvement. In SSc patients without cardiopulmonary involvement AD is associated with better exercise tolerance and cardiac function during physical effort. PubMed, Clin Exp Rheumatol, 05/04/2018. (Also see Brain Involvement)
Cardiometabolic Disorders in Psoriatic Disease (PsD). These findings highlight the importance of controlling disease activity as potential target that could lead to reduced cardiovascular risk in patients with PsD. PubMed, Curr Rheumatol Rep, 2017 Aug 26;19(10):63. (Also see Psoriasis and Psoriatic Arthritis)
Cardiac Involvement in Granulomatosis with Polyangiitis (GPA) : a magnetic resonance imaging study of 31 consecutive patients. This unique non–invasive technique may provide information with important clinical implications for the accurate early assessment of cardiac lesions in GPA patients and for detecting cumulative, irreversible damage. PubMed, Rheumatology (Oxford), 2017 Jun 1;56(6):947-956 (Also see Granulomatosis with Polyangiitis)
Hot flashes at younger ages may signal higher heart risk later. Women who start having hot flashes in their 40s and early 50s had signs of poorer blood vessel health in a recent study and may be at a higher risk of cardiovascular disease later on, researchers say. Reuters Health, 04/21/2017.
Nocturia in Patients With Sleep-Disordered Breathing (SDB) and Cardiovascular Disease (CVD). Continuous positive airway pressure has the potential to reduce nocturia and risk factors for SDB, which may be beneficial in older men with CVD and obstructive sleep apnea. PubMed, Circ J. (Also see Sleep Apnea)
Myopathies related to systemic sclerosis: a case-control study of associated clinical and immunological features. Heart monitoring of SSc patients with myopathy should be undertaken regularly because of the association of myocardial and skeletal myopathies in such patients. PubMed, Scand J Rheumatol. (Also see Myopathies)
Systemic Scleroderma Cardiac (Heart) Involvement. The systemic forms of scleroderma can cause cardiac (heart) problems. One of the earliest symptoms reported by diffuse systemic scleroderma patients is heart irregularities. ISN.
Carotid Artery Disease
Stroke and TIA
Vascular Disease and Systemic Scleroderma. The vascular system is our circulatory system. It consists of all the vessels that carry blood and lymph through the body, to and from organs. Vessels include arteries, veins, and capillaries. Any condition that affects the vascular system, all of in part, is considered a vascular disease. ISN.
Vascular in Scleroderma
Types in Scleroderma
In Other CTDs
Complications with Systemic Scleroderma Cardiac (Heart) Involvement include atrioventricular heart block, cardiogenic shock, myocardial infarction, and skeletal myopathy. ISN.
Aortic Valve Insufficiency
Atrioventricular Heart Block
Diagnosis of Systemic Scleroderma Cardiac (Heart) Involvement. It is common for patients with systemic scleroderma to develop heart involvement even without any overt cardiac symptoms, so mandatory assessment of systemic scleroderma heart involvement requires a thorough baseline screening and follow-up monitoring. ISN.
MRI and CV-MRI
Treatments for Systemic Scleroderma Cardiac (Heart) Involvement include Bosentan, and calcium channel blockers such as nicardipine (Cardene) and nifedipine (Adalat, Procardia). ISN.
Calcium Channel Blockers
Coronary Artery Bypass
Research about Systemic Scleroderma Heart Involvement. Topics include antibodies, autoimmunity, case studies, and causes of scleroderma heart involvement. ISN.
Autoimmunity and Heart Disease
|Causes of Heart Disease|
Anastasia: Surviving Granddaughter of a Diffuse Scleroderma Patient Traveling to a different hospital finally we heard scleroderma…
Angela S: Overlap Syndrome I am twenty-five years old and I was diagnosed with polymyositis and scleroderma, rheumatoid arthritis, mitral valve prolapse, a heart murmur, and pericarditis…
Angiola: Progressive Systemic Scleroderma (Italy) I would very much like to find other people that find themselves in a similar situation…
We have the world's best supporters! See ISN News.
SCLERO.ORG is the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses. We are a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team. Donations may also be mailed to: