Systemic sclerosis (SSc), commonly known as scleroderma, can cause dry mouth. Many scleroderma patients also have Sjogren's syndrome, which can cause dry mouth, too. Many medications cause dry mouth as a side effect, and antibiotics encourage the growth of yeast.
These things make systemic scleroderma patients more prone to getting Candida (yeast) infections. Candida can cause oropharyngeal candidiasis (thrush), and vaginal yeast infections. (Also see Scleroderma Dental Involvement, What is Scleroderma?, Types of Scleroderma, Systemic Sclerosis, and Sjogren's Syndrome)
Symptoms of Oral Thrush. Initially, you may not have noticeable oral thrush symptoms. Symptoms include: Creamy, white lesions on your tongue, inner cheeks and sometimes on the roof of your mouth, gums and tonsils; Lesions with a cottage cheese-like appearance; Pain; Slight bleeding if the lesions are rubbed or scraped; Cracking at the corners of your mouth; A cottony feeling in your mouth; Loss of taste. Mayo Clinic.
FDA Accepts Drug Application For Miconazole Lauriad(R) To Treat Oropharyngeal Candidiasis (OPC). OPC, familiarly known as thrush, is an oral fungal infection that results in lesions and inflammation in the mouth, and includes symptoms such as soreness, burning and/or altered taste most common in individuals with weakened immune systems. Upon FDA approval, this would be the first oral miconazole therapy available in the U.S. Medical News Today. 08/20/09.
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