Hello, I am Dr. Liz Irvin, your ISN Guide to Eye Involvement. In addition to helping Dr. C. Stephen Foster develop resources for this section of the ISN website, I am happy to try to respond to questions that you may have or to redirect you to resources that may be helpful. Email [email protected].
Normal Tension Glaucoma
Other Eye Diseases of Scleroderma
Eyes in Rheumatic Diseases
Eye symptoms and diseases that may be related to scleroderma include normal tension glaucoma, autoimmune iritis or uveitis, and types of optic neuropathy.
A Patient Guide to Ocular Inflammatory Disease. This is an online guide, covering symptoms, diagnosis and treatment for inflammatory eye diseases. In addition, printed copies of this guide can be requested free of charge from the Ocular Immunology and Uveitis Foundation. (Also see Dr. C. Stephen Foster, ISN Medical Advisory Board)
Normal Tension Glaucoma. Normal Tension Glaucoma (NTG) is when the optic nerve is damaged even though the pressure inside of the eye is normal. ISN.
NTG and Scleroderma
|Symptoms and Diagnosis
Autoimmune Iritis or Uveitis. When inflammation affects the eyes, it is called different things depending on which part of the eye it affects (the iris or the uvea). ISN.
Optic Neuropathy is a general term used for damage to the optic nerve regardless of the cause of the damage. ISN.
|Overview||Optic Neuropathy and Scleroderma|
Case Report: Surgical management of raised intra–ocular tension in the hostile ocular surface – recurrent tube erosion in a patient with systemic sclerosis. In patients with systemic disease such as scleroderma, pre–operative immunosuppression helps to reduce the of erosion in difficult cases. PubMed, BMC Ophthalmol.
Evaluation of Changes in Corneal Biomechanics in Patients with Systemic Sclerosis. In the course of the disease SSc leads to various alterations in connective tissue, which can also involve corneal tissue. PubMed, Klin Monbl Augenheilkd, 03/07/2018.
Case Report Highlights Acute Central Retinal Vein Occlusion (CRVO) in Scleroderma Patient The research team thoroughly analyzed other causes of CRVO besides scleroderma, concluding that scleroderma was the most likely cause for this patient’s condition. Scleroderma News.
Prospective study to evaluate the clinical and radiological outcome of patients with scleroderma of the face. Patients with localized scleroderma of the face have a high prevalence of neurological and ophthalmological changes. All cases of localized scleroderma of the face should be thoroughly examined for the presence of systemic changes. PubMed. (Also see Types of Scleroderma, Localized Scleroderma, Neurological Involvement)
(Case Report) Pellucid marginal degeneration and scleroderma. Pellucid marginal degeneration is characterized by non-inflammatory and progressive peripheral corneal thinning inferiorly, often with high against-the-rule astigmatism. PubMed, Clin Exp Optom. 2004 May;87(3):180-4.
Sclerokeratitis and facial skin lesions: a case report of pyoderma gangrenosum and its response to dapsone therapy. Pyoderma gangrenosum is a rare autoimmune disorder that can affect the eye. Biopsy of affected tissue is the key to diagnosis. Immunomodulating therapy can be a useful adjunct to the traditional steroid therapy. PubMed, Cornea, 2007 Feb;26(2):215-9.
Intact Calibers of Retinal Vessels in Patients with Systemic Sclerosis (SSc). The evidence that retinal microcirculation is spared in SSc suggests that fibroproliferative vasculopathy may depend on specific cellular or soluble factors not present in the retinal environment. PubMed, J Rheumatol, 02/01/2015.
(Case Reports) Acute retinal artery occlusion in systemic sclerosis: A rare manifestation of systemic sclerosis fibroproliferative vasculopathy. We describe the clinical features, laboratory and ancillary examinations of the three patients with SSc who developed acute unilateral blindness. Seminars in Arthritis and Rheumatism.
LASIK in Autoimmune Disease
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