Tadalafil causes blood vessels to relax, thus improving circulation and reducing blood pressure in the lungs. It is also used to treat erectile dysfunction, under the brand name Cialis, but in much smaller doses than for PAH.
Tadalafil (ADCIRCA®) is a pill which is usually taken once a day for PAH. It is in a class of drugs called phosphodiesterase-5 Inhibitors (PDE 5 Inhibitors). ADCIRCA® (tadalafil) is manufactured by Eli Lilly and Company, and marketed by Lung Biotechnology PBC and United Therapeutics Corporation.
U.S. Food and Drug Administration Approves New Treatment Combination of Gileadís Letairis® with Tadalafil for Pulmonary Arterial Hypertension (WHO Group 1). The U.S. Food and Drug Administration (FDA) has approved the use of Letairis® (ambrisentan) in combination with tadalafil for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability. Gilead, 10/02/2015. (Also see: Letairis)
(Update) Sara P: CREST Syndrome I am still doing well. Iíve been stable on the PAH meds, Opsumit and ADCIRCA... Posted 02/16/2018.
Many thanks to our recent donors, Jack and Elizabeth Lewis, Chris Dokter, Margaret Roof, Network for Good, PayPal Charitable Giving Fund, United Way Snohomish and Arnold Slotkin. See ISN News for more donors. Click Here to Donate.
TOLL FREE HOTLINE, U.S. and Canada: 1-800-564-7099
Ask for our Free Info Packet by email or postal mail!
SCLERO.ORG is the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses.
We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to: