Diagnosis of Primary vs Secondary
|Raynaud's Secondary to Scleroderma
Raynaud's Secondary to Other Diseases
When Raynaud's appears by itself, without any other medical condition, it is called Primary Raynaud's, or Raynaud's Disease. More than 80% of people with Raynaud's have it by itself, not caused by any serious underlying illness. In primary Raynaud's, the blood vessels return to normal afterwards. (Also see What is Raynaud's?)
When Raynaud's appears along with autoimmune diseases such as scleroderma, systemic lupus erythematosus, or rheumatoid arthritis, it is called Secondary Raynaud's, or Raynaud's Phenomenon. (Also see What is Scleroderma?, Lupus, and Rheumatoid Arthritis)
Raynaud's occurs in about 10% of the general population, but only about 20% of people with Raynaud's have an underlying illness.
Thumb Involvement in Raynaud's Phenomenon as an Indicator of Underlying Connective Tissue Disease. Thumb involvement is one of a number of clinical indicators that should alert the clinician to the possibility of an underlying connective tissue disease/disorder. Batsi Chikura. JRheum. March 1, 2010.
Nailfold Capillaroscopy for Raynaud's Secondary to Scleroderma. Nailfold capillaroscopy can determine whether or not Raynaud's is secondary to an illness such as scleroderma. ISN.
Low Risk Factors for Systemic Sclerosis
High Risk Factors for Systemic Sclerosis
|Raynaud's Secondary to Other Diseases
Research on Capillaroscopy/SSc
Vascular Disease and Scleroderma
Nailfold Capillaroscopy for Raynaud's Secondary to Other Diseases. Nailfold capillaroscopy can also be useful for the diagnosis of secondary Raynaud's due to diseases other than scleroderma, including glaucoma, graft vs. host disease, primary pulmonary hypertension, rheumatoid arthritis, and vascular diseases. ISN.
Graft vs. Host Disease (GVHD)
|Primary Pulmonary Hypertension
SCLERO.ORG was the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses from 1998 to 2021. It was a grassroots movement from the original Scleroderma from A to Z web site, which was founded by Shelley Ensz. We were a 501(c)(3) U.S.-based public charitable foundation. We closed this web site and our nonprofit agency in April 2021.