Nailfold videocapillaroscopy can be used to assess the digital ulcer risk in people who have systemic sclerosis (SSc, scleroderma). Nailfold studies are also useful for diagnosis of systemic scleroderma. (Also see Fingernails, Fingerprints, Nailfolds, and Cuticles)
Progression of nailfold capillaroscopic patterns and correlation with organ involvement in systemic sclerosis: a 12 year study. This longitudinal study confirms over a 12-year follow-up the evolution of specific NVC patterns associated with the progressive severity of organ involvement in SSc patients in a standard clinical care setting. PubMed, Rheumatology (Oxford), 2020 May 1;59(5):1051-1058. (Also see Antibodies and Scleroderma Cardiac (Heart) Involvement)
Nailfold Videocapillaroscopy (NVC) is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis (SSc) and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients (ILD). NVC should be considered in the diagnostic assessment of ILD patients regardless of the presence of Raynaudís Phenomenon. PubMed, Diagnostics (Basel), 2020 Apr 25;10(5). (Also see Pulmonary Fibrosis Diagnosis)
Capillaroscopy changes are associated with disease progression in patients with early systemic sclerosis (SSc): A prospective study. An active or a late pattern on capillaroscopy was an independent predictive risk factor for the development of SSc. PubMed, Int J Rheum Dis, 05/02/2019.
Late nailfold videocapillaroscopy (NVC) patterns associated with hand calcinosis and acro-osteolysis in systemic sclerosis (SSc). Acro–osteolysis and calcinosis are independently associated with the late NVC pattern, and particularly with severe capillary loss. PubMed, Arthritis Care Res (Hoboken). (Also see Bone Resorption in SSc and Calcinosis)
Nailfold capillaroscopic (NVC) parameters and skin telangiectasia patterns in patients with systemic sclerosis. The severity of nailfold microangiopathy seems to correlate in SSc patients with both progressive cutaneous microvascular abnormalities and Medsger's severity score, as evaluated by NVC analysis and dermoscopy. PubMed, Microvasc Res. (Also see Telangiectasia)
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