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Wound Healing in Systemic Scleroderma

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer


Wounds are supposed to heal — not stay the same or get worse.
So the choice is very simple — hire a doctor, or a hearse!

Wound healing can be a real challenge for many systemic scleroderma patients. Wounds include accidental cuts and abrasions, puncture wounds, and microvascular damage such as digital ulcers. Any wound that does not show improvement after a usual period of time should be brought to your doctor's attention.

They used to advise all scleroderma patients to avoid surgery whenever possible, due to concerns about wound healing. Now that is not a blanket recommendation, but rather is an issue to be considered on an individual basis. (Also see What is Scleroderma?, Digital Ulcer Treatments and Gangrene)

Anti-elastase and anti-collagenase potential of Lactobacilli exopolysaccharides (LEPS) on human fibroblast. By consideration of high anti–collagenase, anti–elastase, antioxidant activity and wound healing of LEPS, they could be considered as good candidate of skin anti–aging agents for tissue engineering and skin regeneration scaffolds. PubMed, Artif Cells Nanomed Biotechnol, 2018 Feb 27:1-11. (Also see Causes of Scleroderma: Fibroblasts)

Calcinosis Cutis: WOC Nurse Management. Despite the lack of a standardized approach to treatment of calcinosis cutis, successful management of these patients was achieved by adhering to evidence-based wound-healing principles. PubMed, J Wound Ostomy Continence Nurs, 2018 Jan/Feb;45(1):83-86. (Also see Calcinosis)

Medical Maggots™ (maggot therapy, maggot debridement therapy, MDT, biotherapy, biosurgery, biodebridement, larval therapy). Maggot therapy is the controlled, therapeutic use of live blow fly larvae ("maggots") to treat skin and soft tissue wounds. Monarch Labs.

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