SCLERO.ORG
Search

Completed: Inconclusive or Difficult to Study

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Bovine Collagen DMSO/MSM

Bovine Collagen for Diffuse Scleroderma

Phase II was completed in April 2005.

A multicenter, randomized, double-blind, placebo-controlled trial of oral type I collagen (CI) treatment in patients with diffuse cutaneous systemic sclerosis: I. oral type I collagen does not improve skin in all patients, but may improve skin in late-phase disease. Although the results from this trial did not meet the primary outcome goals, the findings from exploratory analyses indicated that CI treatment may benefit patients with late-phase dcSSc. This new treatment strategy and preliminary clinical observations in patients with dcSSc need to be corroborated. Postlethwaite AE. Arthritis Rheum. 2008 Jun;58(6):1810-22. (PubMed)

Oral Type 1 Collagen in Scleroderma. This is a 15-month study to find out if taking type I collagen by mouth will improve diffuse systemic sclerosis (scleroderma). We will randomly assign 168 patients to receive type I collagen from cows or a placebo (inactive treatment) for 12 months. Study dates 2000-2005. ClinicalTrials.gov. This was the original study.

DMSO (Dimethyl Sulfoxide) and MSM

No Current Studies; No Enrollment.

DMSO is an interesting treatment, which is difficult to study in double-blind trials. Read the latest DMSO Scleroderma studies and decide for yourself.

Scleredema and diabetic sclerodactyly. A 40-year-old man presented with hardening of the skin of his hands and upper back, which had slowly worsened with time. His medical history included insulin-dependent diabetes mellitus since childhood. This patient has improved with aminobenzoate, colchicine, and DMSO gel. Gruson LM. Dermatol Online J. 2005 Dec 30;11(4):3.

Also see: Interstitial Cystitis.

Also See

Sjögren's Treatments & Clinical Trials
Scleroderma Medical News
Scleroderma Symptoms (treatments are listed for each symptom)

Go to Scleroderma Clinical Trials: Completed, Negative Results
 
United Way of Central New Mexico
United Way of Snohomish County
See ISN News for recent donors, including memorials for
Jim Miller, Arlene Marie Petulla, Frances Maude Baldwin Watson and Rubye Mai Blocker Westmoreland.
Thanks to Winn Schillberg for donating to scleroderma research.
Donate or Shop Now
 

TOLL FREE HOTLINE, U.S. and Canada: 1-800-564-7099
Ask for our Free Info Packet by email or postal mail!

SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to:

International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA
Email [email protected] to request our Welcome email, or to report bad links or to update this page content. Privacy Policy.
 

The most important thing in the world to know about scleroderma is sclero.org!

Donate Now
Copyright 1998-2017, International Scleroderma Network. AKA Scleroderma from A to Z and SCLERO.ORG. All Rights Reserved.