Vaccinations and Scleroderma

Medications for Scleroderma, Arthritis, Autoimmune and Rheumatic Diseases

Author: Janey Willis. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview of Vaccinations and Autoimmunity
Seasonal Flu Vaccination
H1N1 Vaccination
Pneumonia Vaccination


Scleroderma patients should always consult their physician before receiving a vaccination of any kind.

Vaccinations such as flu shots and pneumonia shots are recommended for patients with scleroderma and other autoimmune diseases. However, scleroderma patients should always consult their physician before being vaccinated. (Also see What is Scleroderma?, Medical Overview, and Medications for Scleroderma, Arthritis, Autoimmune and Rheumatic Diseases)

Most People Worldwide Trust That Vaccines Are Safe – But the Number Who Don't Is Concerning. The majority of people worldwide think vaccines are safe, according to a new global survey – but the share of doubters is still high enough to threaten immunity. Time Healthland, 06/19/2019.

Human papillomavirus vaccination and the risk of autoimmune disorders: A systematic review and meta –analysis. No evidence of an association between HPV vaccination and ADs was found. PubMed, Vaccine, 04/26/2019. (Also see Causes of Scleroderma: Vaccinations)

Vaccine–induced autoimmunity: the role of molecular mimicry and immune crossreaction. In this review, we address the concept of molecular mimicry and its application in explaining post vaccination autoimmune phenomena. PubMed, Cell Mol Immunol, 2018 Jun;15(6):586-594. (Also see Causes of Scleroderma: Vaccinations)

Seasonal Flu Vaccination

Flu Vaccine Protects About Half the Time, CDC Says. The current flu vaccine is about so–so – it protects about half of people from infection, the Centers for Disease Control and Prevention says. NBC Health News, 02/16/2017.

H1N1/Flu Vaccination

Experts suggest vaccines for those with chronic illness like heart diseases.

Pandemic non–adjuvanted influenza A H1N1 vaccine in a cohort of patients with systemic sclerosis (SSc). The non–adjuvanted influenza H1N1 virus vaccine proved to be safe and effective, independent of SSc clinical subtype, disease severity or therapy. PubMed, Rheumatology (Oxford), 09/08/2017.

Pneumonia Vaccination

The pneumonia vaccine (pneumococcal vaccine or PPV23 or PPSV) is recommended for adults over 65 and younger persons with chronic illnesses or weakened immune systems. According to UpToDate® a 2009 meta-analysis on the efficacy of PPV23 suggests that the pneumococcal vaccination appears to be more beneficial in the prevention of invasive pneumococcal disease, rather than in the prevention of pneumonia. Scleroderma patients should discuss the pros and cons of this vaccine with their physicians. ISN.

Pneumococcal Vaccination (Pneumonia Vaccination). Pneumococcal vaccination is a method of preventing a specific type of lung infection (pneumonia) that is caused by Pneumococcus bacterium. There are more than 80 different types of pneumococcus bacteria-23 of these are covered in the current vaccination.

Superbug review says more vaccines needed to reduce antibiotic use. More use of vaccines would reduce the need to use antibiotics and help fight the rise of drug–resistant superbug infections, according to a British government–commissioned review of the threat. Reuters Health, 02/11/2016. (Also see Arthritis Treatments – General)

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