Vaccinations and Scleroderma

Medications for Scleroderma, Arthritis, Autoimmune and Rheumatic Diseases

Author: Janey Willis. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview of Vaccinations and Autoimmunity
Seasonal Flu Vaccination
H1N1 Vaccination
Pneumonia Vaccination


Scleroderma patients should always consult their physician before receiving a vaccination of any kind.

Vaccinations such as flu shots and pneumonia shots are recommended for patients with scleroderma and other autoimmune diseases. However, scleroderma patients should always consult their physician before being vaccinated. (Also see What is Scleroderma?, Medical Overview, and Medications for Scleroderma, Arthritis, Autoimmune and Rheumatic Diseases)

Autoimmune connective tissue diseases and vaccination. As yet, no conclusive evidence supports a causal relationship between vaccination and autoimmune diseases. PubMed, Postepy Hig Med Dosw (Online), 2015 Dec 31;69:1530-8. (Also see Causes of Scleroderma: Vaccinations)

Vaccines, adjuvants and autoimmunity. Vaccinomics is a field that may bring to light novel customized, personalized treatment approaches in the future. PubMed, Pharmacol Res, 2015 Oct;100:190-209. (Also see Causes of Scleroderma: Vaccinations)

Predicting post-vaccination autoimmunity: who might be at risk? By defining individuals at risk we may further limit the number of individuals developing post-vaccination autoimmune/inflammatory syndrome induced by adjuvants – ASIA syndrome. PubMed, Pharmacol Res, 2015 Feb;92:18-22. (Also see Causes of Scleroderma: Vaccinations)

Vaccination and Induction of Autoimmune Diseases (AID). Cases of AID triggered by vaccines are highly rare and raise questions about the interaction between vaccines and/or their adjuvants and the genetic context of autoimmune disease. PubMed, Inflamm Allergy Drug Targets, 2015;14(2):94-8. (Also see Causes of Scleroderma: Vaccinations)

Seasonal Flu Vaccination

Flu Vaccine Protects About Half the Time, CDC Says. The current flu vaccine is about so–so – it protects about half of people from infection, the Centers for Disease Control and Prevention says. NBC Health News, 02/16/2017.

H1N1/Flu Vaccination

Experts suggest vaccines for those with chronic illness like heart diseases.

Pandemic non–adjuvanted influenza A H1N1 vaccine in a cohort of patients with systemic sclerosis (SSc). The non–adjuvanted influenza H1N1 virus vaccine proved to be safe and effective, independent of SSc clinical subtype, disease severity or therapy. PubMed, Rheumatology (Oxford), 09/08/2017.

Pneumonia Vaccination

The pneumonia vaccine (pneumococcal vaccine or PPV23 or PPSV) is recommended for adults over 65 and younger persons with chronic illnesses or weakened immune systems. According to UpToDate® a 2009 meta-analysis on the efficacy of PPV23 suggests that the pneumococcal vaccination appears to be more beneficial in the prevention of invasive pneumococcal disease, rather than in the prevention of pneumonia. Scleroderma patients should discuss the pros and cons of this vaccine with their physicians. ISN.

Pneumococcal Vaccination (Pneumonia Vaccination). Pneumococcal vaccination is a method of preventing a specific type of lung infection (pneumonia) that is caused by Pneumococcus bacterium. There are more than 80 different types of pneumococcus bacteria-23 of these are covered in the current vaccination.

Superbug review says more vaccines needed to reduce antibiotic use. More use of vaccines would reduce the need to use antibiotics and help fight the rise of drug–resistant superbug infections, according to a British government–commissioned review of the threat. Reuters Health, 02/11/2016. (Also see Arthritis Treatments – General)

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