SCLERO.ORG
Search

Juvenile Scleroderma Research

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview
Nailfold Capillaroscopy
Prognosis and Mortality
Treatments

Overview

When any form of scleroderma (either localized or systemic) occurs in children, it is also called Childhood Scleroderma or Juvenile Scleroderma.

Nailfold Capillaroscopy in Juvenile Scleroderma

A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis (SSc): A EUSTAR exploratory study. This is the first exploratory study on the comparison of capillaroscopy between juvenile–onset and adult–onset SSc in adulthood. PubMed, Microvasc Res, 2015 Nov;102:19-24.

Prognosis and Mortality in Juvenile Scleroderma

Juvenile Systemic Sclerosis Prognosis. Although a severely debilitating disease with significant morbidity and mortality, the prognosis of children with JSSc has been reported to be better than in adult patients with systemic sclerosis. Medscape.

Treatments for Juvenile Scleroderma

UVA1 phototherapy is now the recommended first-line treatment for localized scleroderma, such as morphea and linear.

For UVA1 treatment, first contact your doctor to see if it they will recommend it for you. It is not used for lichen sclerosus that is on the genital area. If they recommend and prescribe it for you, try to find UVA1 facilities near you. Some dermatology offices (usually large offices or with major health centers) have UVA1 equipment (not UVB). It may also be possible to buy UVA1 phototherapy equipment for home use. It is manufactured by Daavlin and distributed worldwide. Home users must be monitored by a physician, who will prescribe the necessary dosage and monitor for possible side-effects, such as skin cancer.

Fibrocell’s FX-013 Therapy Wins FDA Rare Pediatric Disease Designation for Localized Scleroderma. The U.S. Food and Drug Administration (FDA) has granted Rare Pediatric Disease Designation to FX-013, a Fibrocell gene therapy candidate to treat children with moderate to severe localized scleroderma. Scleroderma News, 06/13/2017. (Also see Clinical Trials)

Go to Localized: Linear Scleroderma
 

Many thanks to our recent donors, Jack and Elizabeth Lewis. See ISN News for more donors. Click Here to Donate.

 

TOLL FREE HOTLINE, U.S. and Canada: 1-800-564-7099
Ask for our Free Info Packet by email or postal mail!

SCLERO.ORG is the world's leading nonprofit for trustworthy research, support, education and awareness for scleroderma and related illnesses.

We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to:

International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA
Email [email protected] to request our Welcome email, report bad links, or update page content. Disclaimer. Privacy Policy.
 

The most important thing in the world to know about scleroderma is sclero.org!

DONATE