Connective tissue diseases are complex illnesses that can affect any part of the body, such as dermatomyositis/polymyositis, lupus, mixed connective tissue disease, rheumatoid arthritis, scleroderma, and Sjogren's.
Connective Tissue Disease. A connective tissue disease is any disease that has the connective tissues of the body as a primary target of pathology. MedicineNet.com
Thoracic Manifestations of Connective Tissue Diseases. The most important thoracic manifestations of CTDs are interstitial lung disease and pulmonary arterial hypertension, with nonspecific interstitial pneumonia being the most common pattern of interstitial lung disease. PubMed, Curr Probl Diagn Radiol, 2014 Aug 14.
Biomarkers in connective tissue diseases. This review describes select current biomarkers that aid in the diagnosis and treatment of several major systemic autoimmune connective tissue disorders and also newly proposed biomarkers. PubMed, J Allergy Clin Immunol, 2017 Dec;140(6):1473-1483.
Acute Respiratory Events in Connective Tissue Disorders (CTDs). In CTDs the lungs significantly contribute to morbidity and mortality, since they constitute a common site of disease involvement. PubMed, Respiration, 03/04/2016.
Investigation of Lung Involvement in Connective Tissue Disorders (CTD). The investigation of lung involvement in CTDs requires adequate skills in the ambit of a multidisciplinary approach and an extended spectrum of diagnostic tools. PubMed, Respiration, 06/26/2015. (Also see Pulmonary Fibrosis Diagnosis)
Clinical characteristics and survival in idiopathic pulmonary fibrosis (IPF) and connective tissue disease-associated usual interstitial pneumonia (CTD-UIP). Although the survival of CTD-UIP patients was similar compared with that of IPF/UIP patients, it appears that Undifferentiated Connective Tissue Disease influences the survival rate of CTD-UIP patients. Journal of Thoracic Disease, 04/03/2015. (Also see Pulmonary Fibrosis Prognosis)
Histopathology of Lung Disease in the Connective Tissue Diseases (CTD). This article will cover the pulmonary pathologies seen in rheumatoid arthritis, systemic sclerosis, myositis, systemic lupus erythematosus, Sjögren syndrome, and mixed CTD. Rheumatic Disease Clinics of North America, 03/06/2015. (Also see Pulmonary Fibrosis Diagnosis)
Interstitial lung disease (ILD) in connective tissue disease (CTD) - mechanisms and management. Data from treatment trials in systemic sclerosis support the use of immunosuppressive therapy, with the treatment benefit largely relating to the prevention of progression of lung disease. PubMed, Nat Rev Rheumatol, 2014 Sep 30. (Also see Pulmonary Fibrosis Treatments)
Interstitial Lung Disease (ILD) in Undifferentiated Forms of Connective Tissue Disease(CTD). There is much uncertainty and controversy surrounding the suggestive forms of CTD-associated ILD (CTD-ILD) and prospective studies are needed to provide a better understanding of the natural history of these cohorts. PubMed, Arthritis Care Res, 2014 Jul 21. (Also see Lung Involvement Prognosis)
Reconciling Healthcare Professional and Patient Perspectives in the Development of Disease Activity and Response Criteria in Connective Tissue Disease-related Interstitial Lung Diseases (CTD-ILD). Efforts described here demonstrate unequivocally the value and influence of patient involvement on core set development. PubMed, J Rheumatol, 2014 Feb 1. (Also see Pulmonary Fibrosis)
Connective tissue disease (CTD) increases risk for cardiovascular problems. The findings show that CTD is associated with higher prevalence of atherosclerotic cardiovascular disease and these insights could be used to improve how patients with a wide range of connective tissue diseases are evaluated. University of Chicago Medical Center, 02/05/2016.
How are cancer and connective tissue diseases (CTDs) related to sarcoidosis? The association between sarcoidosis and both cancer and CTDs may yield important insights into the immunopathogenesis of all three diseases. PubMed, Curr Opin Pulm Med, 2015 Sep;21(5):517-24. (Also see Sarcoidosis and Cancer)
Determining the necessity for right heart catheterization (RHC) in pulmonary hypertension (PH) associated with connective tissue diseases (CTD) assessed by echocardiography. These findings demonstrate the necessity for RHC and differences in prognosis of PH in CTD. Wiley Online Library, 10/07/2015. (Also see Pulmonary Hypertension Diagnosis)
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